Lhermitte M, Chiche D, Houdret N, Roussel P
Unité des Protéines, INSERM (n.16), Lille.
Pathol Biol (Paris). 1991 May;39(5):500-2.
Cefuroxime binding to soluble bronchial macromolecules has been performed in vitro with preparations obtained from ten patients. Cefuroxime at various concentrations have been added to soluble macromolecules (10 g/l). Free cefuroxime has been obtained by equilibrium dialysis and measured by HPLC. Results show that cefuroxime binding is about 30% of total antibiotic.
已使用从10名患者获得的制剂在体外进行了头孢呋辛与可溶性支气管大分子的结合实验。将不同浓度的头孢呋辛添加到可溶性大分子（10 g/l）中。通过平衡透析获得游离头孢呋辛，并通过高效液相色谱法进行测定。结果表明，头孢呋辛的结合率约为抗生素总量的30%。
