Chen Cheng-Hsu, Wen Mei-Chin, Cheng Chi-Hung, Wu Ming-Ju, Yu Tung-Min, Chuang Ya-Wen, Shu Kuo-Hsiung
Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.
J Chin Med Assoc. 2008 Sep;71(9):477-80. doi: 10.1016/S1726-4901(08)70152-7.
Tinea capitis rarely occurs in renal transplant recipients. We report this living-related renal transplant patient receiving cyclosporine-based therapy who initially presented with severe exfoliation of the scalp with yellowish-white scales and marked hair loss. The lesions extended to the frontal area and both cheeks, resulting in several skin ulcers with perifocal erythematous inflammatory changes, and palpable cervical lymph nodes. A biopsy of a skin lesion revealed fungal infection and culture yielded Microsporum canis. The patient mentioned an outbreak of ringworm in her breeding dogs during this period. After adequate treatment of the patient and her infected animals with griseofulvin and disinfection of the environment, her skin lesions resolved dramatically, with regrowth of hair.
头癣在肾移植受者中很少见。我们报告了这名接受基于环孢素治疗的亲属活体肾移植患者,其最初表现为头皮严重脱屑,伴有黄白色鳞屑和明显脱发。病变扩展至额部和双侧脸颊,导致多处皮肤溃疡,伴有病灶周围红斑性炎症改变,且可触及颈部淋巴结。皮肤病变活检显示真菌感染,培养结果为犬小孢子菌。患者提到在此期间她饲养的狗爆发了癣病。在用灰黄霉素对患者及其感染动物进行充分治疗并对环境进行消毒后,她的皮肤病变显著消退,头发重新生长。