Cai Qiangjun, Skelding Kimberly, Armstrong Arthur, Desai Dipan, Wood G Craig, Blankenship James
Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania 17822, USA.
Angiology. 2009 Apr-May;60(2):141-7. doi: 10.1177/0003319708321587. Epub 2008 Sep 25.
Limited data exist regarding the predictors of long-term clinical outcomes following elective percutaneous coronary intervention (PCI) in the current era of stenting. The authors investigated the predictors of major adverse cardiac events (MACE) and clinical restenosis in 740 consecutive patients who underwent successful elective PCI with bare metal stents (BMSs) or drug-eluting stents (DESs). At 30-month follow-up, compared with BMS recipients, DES recipients had a significantly lower rate of MACE, which was mainly driven by a decreased repeat target vessel PCI. The rate of 30-month clinical restenosis was significantly lower in DES recipients. The authors conclude that baseline clinical, angiographic, and procedural characteristics determine long-term MACE and clinical restenosis after elective PCI, with DES being the independent predictor for both.
在当前支架置入时代，关于择期经皮冠状动脉介入治疗（PCI）后长期临床结局的预测因素的数据有限。作者调查了740例连续接受裸金属支架（BMS）或药物洗脱支架（DES）成功择期PCI患者的主要不良心脏事件（MACE）和临床再狭窄的预测因素。在30个月的随访中，与接受BMS的患者相比，接受DES的患者MACE发生率显著更低，这主要是由于再次靶向血管PCI减少所致。接受DES的患者30个月临床再狭窄率显著更低。作者得出结论，基线临床、血管造影和手术特征决定了择期PCI后的长期MACE和临床再狭窄，DES是两者的独立预测因素。
