Checchi L, Biagini G, Zucchini C, De Luca M
University of Bologna, School of Dentistry, Italy.
Quintessence Int. 1991 Jun;22(6):483-9.
The interdental papilla is the anatomic site most susceptible to periodontal disease. The gingival epithelium plays an important role as a barrier to protect the underlying connective tissue from exogenous noxious agents. A study was undertaken to evaluate the papillary epithelial response to reconstructive stresses conducted by gingival brushing (oral therapy) and scaling and root planing, intended to induce a keratinization associated with reduction or resolution of connective tissue inflammation. Results showed that patients who prolonged the interproximal hygiene practices for more than 30 minutes a day achieved a satisfactory keratinization of the papillary gingival epithelium.
龈乳头是最易患牙周病的解剖部位。牙龈上皮作为一种屏障，在保护其下方的结缔组织免受外源性有害物质侵害方面发挥着重要作用。开展了一项研究，以评估龈乳头上皮对牙龈刷牙（口腔治疗）以及龈下刮治和根面平整所产生的重建性压力的反应，这些操作旨在诱导与结缔组织炎症减轻或消退相关的角化。结果显示，每天将邻面卫生操作延长至30分钟以上的患者，其龈乳头牙龈上皮实现了令人满意的角化。
