犬甲状腺腺瘤复杂核型变化的特征分析

Characterisation of complex karyotype changes in a canine thyroid adenoma.

作者信息

Mayr B, Schleger W, Loupal G, Burtscher H

机构信息

Institute of Animal Breeding and Genetics, Veterinary University, Vienna, Austria.

出版信息

Res Vet Sci. 1991 May;50(3):298-300. doi: 10.1016/0034-5288(91)90127-a.

DOI:10.1016/0034-5288(91)90127-a

PMID:1882136

Abstract

A 14-year-old German shepherd dog developed an alveolar adenoma of the thyroid. The cytogenetic evaluation of the tumour cells showed two ranges of chromosome numbers. Centric fusions 2/32, 5/26, 6/11, 8/11, 9/23 and 14/31 were G-band identified in this complex change of karyotype.

摘要

一只14岁的德国牧羊犬患上了甲状腺肺泡腺瘤。对肿瘤细胞进行的细胞遗传学评估显示出两个染色体数范围。在这种复杂的核型变化中，通过G带鉴定出了2/32、5/26、6/11、8/11、9/23和14/31的着丝粒融合。