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[重症肌无力与妊娠:文献综述及2例报告]

[Myasthenia gravis and pregnancy: review of the literature and report of 2 cases].

作者信息

Cecatti J G, Pereira R I, Vial J S, Barini R

机构信息

Departamento de Tocoginecologia, Campinas, SP.

出版信息

Rev Paul Med. 1991 Jan-Feb;109(1):41-6.

PMID:1882173
Abstract

Two cases of women with myasthenia gravis are presented. These women had three pregnancies followed by the authors, and description is made of clinical follow-up, therapeutic complications, termination of pregnancy, puerperal and perinatal outcome. A review of the literature is made due to the rarity of this condition and emphasis is given to the specialized knowledge required to adequately manage these cases. Myasthenia gravis, when associated to pregnancy, presents aspects that make it a high risk disease, decompensations of myasthenia being more common. Aspects relative to diagnosis and therapy of myasthenia in pregnancy and in the newly-born are reviewed, and considerations about anesthesia in the myasthenic pregnant woman.

摘要

本文报告了两例重症肌无力女性患者。这两名女性患者在作者的跟踪下经历了三次妊娠,并对临床随访、治疗并发症、妊娠终止、产后及围产期结局进行了描述。鉴于这种情况较为罕见,因此对文献进行了综述,并强调了妥善处理这些病例所需的专业知识。重症肌无力与妊娠相关时,会呈现出一些使其成为高危疾病的特征,肌无力失代偿更为常见。本文回顾了妊娠及新生儿重症肌无力的诊断和治疗相关问题,并对重症肌无力孕妇的麻醉问题进行了探讨。

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