Machado Sergio, Cunha Marlo, Portella Cláudio Elidio, Silva Julio Guilherme, Velasques Bruna, Bastos Victor Hugo, Budde Henning, Pompeu Fernando, Basile Luis, Cagy Mauricio, Piedade Roberto, Ribeiro Pedro
Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Rio de Janeiro, Brazil.
Neurosci Lett. 2008 Nov 28;446(1):7-10. doi: 10.1016/j.neulet.2008.09.036. Epub 2008 Sep 19.
The study aimed to elucidate electrophysiological and cortical mechanisms involved in anticipatory actions when healthy subjects had to catch balls in free drop; specifically through quantitative electroencephalography (qEEG) alpha absolute power changes. Our hypothesis is that during the preparation of motor action (i.e., 2s before ball's drop) occurred integration among left medial frontal, left primary somatomotor and left posterior parietal cortices, showing a differentiated activity involving expectation, planning and preparedness. This hypothesis supports a lateralization of motor function. Although we contend that in right-handers the left hemisphere takes on a dominant role for the regulation of motor behavior. The sample was composed of 23 healthy subjects (13 male and 10 female), right handed, with ages varying between 25 and 40 years old (32.5+/-7.5), absence of mental and physical illness, right handed, and do not make use of any psychoactive or psychotropic substance at the time of the study. The experiment consisted of a task of catching balls in free drop. The three-way ANOVA analysis demonstrated an interaction between moment and position in left medial frontal cortex (F3 electrode), somatomotor cortex (C3 electrode) and posterior parietal cortex (P3 electrode; p < 0.001). Summarizing, through experimental task employed, it was possible to observe integration among frontal, central and parietal regions. This integration appears to be more predominant in expectation, planning and motor preparation. In this way, it established an absolute predominance of this mechanism under the left hemisphere.
该研究旨在阐明健康受试者在自由落体状态下接球时预期动作所涉及的电生理和皮层机制；具体是通过定量脑电图（qEEG）的阿尔法绝对功率变化来进行研究。我们的假设是，在运动动作准备期间（即球下落前2秒），左内侧额叶、左初级躯体运动皮层和左后顶叶皮层之间发生了整合，表现出涉及预期、计划和准备的不同活动。这一假设支持了运动功能的偏侧化。尽管我们认为在右利手个体中，左半球在运动行为调节中起主导作用。样本由23名健康受试者组成（13名男性和10名女性），均为右利手，年龄在25至40岁之间（32.5±7.5），无精神和身体疾病，右利手，且在研究时未使用任何精神活性或精神otropic物质。实验包括自由落体接球任务。三因素方差分析表明，左内侧额叶皮层（F3电极）、躯体运动皮层（C3电极）和后顶叶皮层（P3电极；p<0.001）的时刻和位置之间存在交互作用。总之，通过所采用的实验任务，可以观察到额叶、中央和顶叶区域之间的整合。这种整合在预期、计划和运动准备中似乎更为突出。通过这种方式，确立了该机制在左半球下的绝对优势。
