Piccioli M, Parisi P, Tisei P, Villa M P, Buttinelli C, Kasteleijn-Nolst Trenité D G A
Department of Neurology, II Faculty of Medicine, La Sapienza University, Rome Italy.
Cephalalgia. 2009 Feb;29(2):194-203. doi: 10.1111/j.1468-2982.2008.01707.x. Epub 2008 Sep 24.
Migrainous headache is reported by patients with photosensitive epilepsy, whereas their relatives complain more often about headache than the relatives of patients with other types of epilepsy. We therefore investigated whether headache itself could be an epileptic symptom related to photosensitivity. Four probands with headache and photosensitive epilepsy were selected. Their first-degree family members were studied using video-EEG with extensive intermittent photic stimulation and pattern stimulation. Nine of the 12 subjects (10 female and two male, mean age 30 years, range 14-46 years) proved to be photosensitive with either focal (n = 5) or generalized (n = 4) epileptiform discharges. In two subjects an ictal recording of headache occurred after visual stimulation. We found evidence that, in specific patients, headache could be an ictal sign of epilepsy. Photic stimulation during EEG recording can contribute to correct diagnosis and lead to the best care and management of the patient.
光敏性癫痫患者会报告偏头痛，而他们的亲属比其他类型癫痫患者的亲属更常抱怨头痛。因此，我们研究了头痛本身是否可能是与光敏性相关的癫痫症状。选择了4名患有头痛和光敏性癫痫的先证者。使用视频脑电图对他们的一级家庭成员进行了广泛的间歇性光刺激和模式刺激研究。12名受试者中的9名（10名女性和2名男性，平均年龄30岁，范围14 - 46岁）被证明对局灶性（n = 5）或全身性（n = 4）癫痫样放电敏感。在两名受试者中，视觉刺激后出现了头痛的发作期记录。我们发现有证据表明，在特定患者中，头痛可能是癫痫的发作期体征。脑电图记录期间的光刺激有助于正确诊断，并为患者提供最佳的护理和管理。
