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[非特异性牙源性感染中需氧菌对化疗的耐药性]

[Resistance to chemotherapy of aerobic bacteria from nonspecific odontogenic infections].

作者信息

Oehring H, Schumann D, Karl P, Knappe U, Gruhn I

出版信息

Zahn Mund Kieferheilkd Zentralbl. 1976;64(6):580-7.

PMID:188271
Abstract

Germs in patients suffering from nonspecific odontogenous infections described in a previous paper were analysed with regard to their resistance to chemotherapy (1964 to 1971). At the same time it was discovered that in the bacteria groups: staphyloccocus aureus, streptococci and pneumococci and enterobacteriaceae plus pseudomonas (344 strains) their sensitivity to penicillin, streptomycin, chloramphenicol, oxytetracyclin, erythromycin, polymyxin B and nifurantin varied in several and significant ways. Significant changes were established in the resistance of staphylococcus aureus to all the potentially effective antibiotics, while from 1969 to 1971 the strains with the least resistance appeared. In the 1970 to 1971 period strepto- and pneumococci showed insensitivity to penicillin and streptomycin more frequently than before. From 1969 to 1971 entero-bacteriaceae and pseudomonas also showed evidence of increasing loss of sensitivity to chloramphenicol and oxytetracyclin, whereas the frequency of strains resistant to polymyxin B and nifurantine diminished. The findings are being discussed.

摘要

针对先前论文中描述的非特异性牙源性感染患者体内的病菌,分析了它们对化疗的耐药性(1964年至1971年)。与此同时,发现在细菌组中:金黄色葡萄球菌、链球菌、肺炎球菌以及肠杆菌科加假单胞菌(344株),它们对青霉素、链霉素、氯霉素、土霉素、红霉素、多粘菌素B和呋喃妥因的敏感性在多个方面存在显著差异。金黄色葡萄球菌对所有潜在有效抗生素的耐药性出现了显著变化,而在1969年至1971年期间出现了耐药性最低的菌株。在1970年至1971年期间,链球菌和肺炎球菌对青霉素和链霉素的不敏感性比以前更为频繁。从1969年至1971年,肠杆菌科和假单胞菌对氯霉素和土霉素的敏感性丧失也有增加的迹象,而对多粘菌素B和呋喃妥因耐药的菌株频率则有所下降。对这些发现进行了讨论。

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