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谷胱甘肽S-转移酶(GSTM1)基因多态性在子宫肌瘤发生发展中的作用。

Role of glutathione S-transferase (GSTM1) gene polymorphism in development of uterine fibroids.

作者信息

de Oliveira Emerson, de Aquino Castro Rodrigo, Vieira Gomes Mariano Tamura, Cotrim Guerreiro da Silva Ismael Dale, Baracat Edmund Chada, Rodrigues de Lima Geraldo, Ferreira Sartori Marair Gracio, Batista Castello Girão Manoel João

机构信息

Department of Gynecology, Federal University of São Paulo, São Paulo, Brazil.

出版信息

Fertil Steril. 2009 Apr;91(4 Suppl):1496-8. doi: 10.1016/j.fertnstert.2008.07.1767. Epub 2008 Oct 1.

Abstract

Glutathione S-transferase (GSTM1) plays an important role in the excretion of catechol estrogens and is therefore a candidate marker for fibroids. However, this case-control study demonstrated no association between GSTM1 polymorphism and the risk of leiomyoma in Brazilian women.

摘要

谷胱甘肽S-转移酶(GSTM1)在儿茶酚雌激素的排泄中起重要作用,因此是子宫肌瘤的一个候选标志物。然而,这项病例对照研究表明,GSTM1基因多态性与巴西女性患平滑肌瘤的风险之间没有关联。

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