MSP I CYP1A1 基因多态性在子宫肌瘤发病机制中的作用。
The role of MSP I CYP1A1 gene polymorphism in the development of uterine fibroids.
机构信息
Department of Gynecology, Federal University of São Paulo, São Paulo, Brazil.
出版信息
Fertil Steril. 2010 Dec;94(7):2783-5. doi: 10.1016/j.fertnstert.2010.05.034. Epub 2010 Jul 1.
Abstract
The cytochrome P-450 1A1 (CYPA1A) gene plays an important role in the metabolization of estrogen and is therefore a candidate marker for fibroids. In a case-control study, we were unable to demonstrate any association between MSP I CYP1A1 polymorphism and the risk of leiomyoma in Brazilian women.
摘要
细胞色素 P-450 1A1（CYPA1A）基因在雌激素代谢中起着重要作用，因此是纤维瘤的候选标志物。在一项病例对照研究中，我们未能证明 MSP I CYP1A1 多态性与巴西女性子宫肌瘤风险之间存在任何关联。
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