Addington Jean, Addington Donald
Department of Psychiatry, University of Calgary, Calgary, Canada.
Schizophr Res. 2008 Dec;106(2-3):363-6. doi: 10.1016/j.schres.2008.08.032. Epub 2008 Oct 1.
Studies defining the course and outcome of individuals experiencing their first episode (FE) of psychosis generally report an improvement in symptoms and functioning. Today, many FE patients are treated in specialized early psychosis programs. Little is known what happens to these individuals after discharge from these programs back to regular services. We report here on the outcomes of the first 200 subjects admitted to a three year specialized first episode service who could be contacted for assessments between 1 and 2 years after discharge. Approximately 50% of those initially assessed in a first episode service were able to be followed for up to 5 years. Results were that, although there was no further improvement in positive symptoms, there was continued improvement in social functioning and signs of improvement in negative symptoms.
关于首次发作(FE)精神病患者病程及预后的研究通常报告称症状和功能有所改善。如今,许多首次发作患者在专门的早期精神病项目中接受治疗。对于这些患者从这些项目出院后回归常规服务时会发生什么,我们知之甚少。我们在此报告首批入住为期三年的专门首次发作服务项目的200名受试者的预后情况,这些受试者在出院后1至2年可被联系进行评估。最初在首次发作服务项目中接受评估的患者中,约50%能够被随访长达5年。结果显示,虽然阳性症状没有进一步改善,但社会功能持续改善,阴性症状也有改善迹象。