Gasparis Antonios P, Labropoulos Nicos, Tassiopoulos Apostolos K, Phillips Brett, Pagan Jose, Ricotta John
Stony Brook University Medical Center, Surgery, Stony Brook, New York, USA.
Vasc Endovascular Surg. 2009 Feb-Mar;43(1):61-8. doi: 10.1177/1538574408323501. Epub 2008 Sep 30.
To provide follow-up in patients treated with pharmacomechanical thrombolysis (PhMT) for lower extremity deep venous thrombosis (DVT).
Retrospective analysis of prospectively collected data. Patients underwent clinical evaluation, duplex ultrasound, venous clinical severity scoring, venous segmental disease scoring, and venous disability scoring.
Fourteen patients were available for evaluation. Median age was 40 years (19-58). Median follow-up was 24 months (13-69 months). Thirteen of 14 patients (93%) had a venous disability score < 1 and 13 of 14 patients (93%) had a venous clinical severity scoring < 5. In all but 1 patient the venous segmental disease scoring score was < 5. All iliac segments were patent, all but 3 patients had partial infrainguinal obstruction and 5 of 14 (36%) had reflux.
Our data demonstrate that the good early clinical results after PhMT can be sustained on longer follow-up and may prevent the development of advanced postthrombotic syndrome.
对接受药物机械性溶栓（PhMT）治疗下肢深静脉血栓形成（DVT）的患者进行随访。
对前瞻性收集的数据进行回顾性分析。患者接受临床评估、双功超声检查、静脉临床严重程度评分、静脉节段性疾病评分和静脉功能障碍评分。
14例患者可供评估。中位年龄为40岁（19 - 58岁）。中位随访时间为24个月（13 - 69个月）。14例患者中有13例（93%）静脉功能障碍评分为<1，14例患者中有13例（93%）静脉临床严重程度评分为<5。除1例患者外，所有患者的静脉节段性疾病评分为<5。所有髂静脉段通畅，14例患者中有11例有部分腹股沟下梗阻，14例中有5例（36%）有反流。
我们的数据表明，PhMT术后良好的早期临床结果在更长时间的随访中可以持续，并可能预防晚期血栓形成后综合征的发生。
