Kamran Mazullah, Guptan Amrit, Bogal Monika
Sinai Medical Center, The Zena and Michael A. Wiener Cardiovascular Institute, The Mt. Sinai Medical Center, Box 1030, One Gustave L. Levy Place, New York, NY 10029, USA.
J Invasive Cardiol. 2008 Oct;20(10):553-9.
Spontaneous coronary artery dissection (SCAD) is a rare but important cause of acute coronary syndromes. SCAD can cause unstable angina, acute myocardial infarction, and sudden death. Predisposing factors include atherosclerosis, the peripartum period, and structural and inflammatory conditions affecting the arterial wall. The diagnosis of coronary dissection is usually made by coronary angiography. Prompt diagnosis and treatment of patients with dissection improves survival. Therapeutic options include medical therapy, percutaneous coronary intervention, and surgery. We present a series of patients with spontaneous coronary artery dissection at our institution. The etiology, pathogenesis, diagnosis, treatment, and prognosis of patients with coronary dissection are reviewed.
自发性冠状动脉夹层（SCAD）是急性冠状动脉综合征的一种罕见但重要的病因。SCAD可导致不稳定型心绞痛、急性心肌梗死和猝死。易感因素包括动脉粥样硬化、围产期以及影响动脉壁的结构和炎症性疾病。冠状动脉夹层的诊断通常通过冠状动脉造影来进行。对夹层患者进行及时诊断和治疗可提高生存率。治疗选择包括药物治疗、经皮冠状动脉介入治疗和手术治疗。我们展示了我院一系列自发性冠状动脉夹层患者。对冠状动脉夹层患者的病因、发病机制、诊断、治疗及预后进行了综述。
