Suppr超能文献

[酸性阴离子和介质酸度对恶性肿瘤特有的免疫球蛋白G转变为水不溶状态过程中pH值的影响]

[Effect of acid anions and medium acidity on pH during a change of immunoglobulin G, peculiar to malignant growth, to water-insoluble state].

作者信息

Nizhinkivs'ka T M, Ivanov O P, Korotkoruchko V P

出版信息

Ukr Biokhim Zh. 1977 May-Jun;49(3):55-60.

PMID:18831
Abstract

Affinity of an acid anion for proteins has a decisive effect on conditions for detecting using an acid medium immunoglobulin G peculiar to the malignant growth in blood serum of patients with cancer. Depending on the protein affinity of the anion of the acid used for the reaction immunoglobulin G appearing in blood of patients with cancer under equal conditions may be in a soluble state or change to a sediment. The presence of salts in the reaction mixture has no effect on conditions of the reaction performance. Exposition of blood sera to the acid medium before titration favours a more distinct detection of the studied protein in blood of patients with cancer.

摘要

酸性阴离子与蛋白质的亲和力对使用酸性介质检测癌症患者血清中恶性肿瘤特有的免疫球蛋白G的条件具有决定性影响。根据用于反应的酸的阴离子与蛋白质的亲和力,在相同条件下癌症患者血液中出现的免疫球蛋白G可能处于可溶状态或转变为沉淀物。反应混合物中盐的存在对反应进行的条件没有影响。滴定前将血清暴露于酸性介质有利于更清晰地检测癌症患者血液中所研究的蛋白质。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验