Peters W
Division of Plastic Surgery, Wellesley Hospital, Toronto, Ontario, Canada.
Ann Plast Surg. 1991 Jun;26(6):564-71. doi: 10.1097/00000637-199106000-00013.
Chemical peeling of facial skin has become a valuable adjunct in the armamentarium of the facial aesthetic surgeon. Among the various techniques available, phenol solutions are the most commonly used. Peeling produces a controlled, partial-thickness chemical burn of the epidermis and the outer dermis. Several techniques are available to "fine tune" the depth of the peel. Regeneration of peeled skin results in a fresh, orderly, organized epidermis. In the dermis, a new 2- to 3-mm band of dense, compact, orderly collagen is formed between the epidermis and the underlying damaged dermis, which results in effective ablation of the fine wrinkles in the skin and a reduction of pigmentation. These clinical and histological changes are long lasting (15-20 years) and may be permanent in some patients. Because of the metabolism and systemic complications of phenol, patient selection should involve systemic evaluation of liver, renal, and cardiac function, as well as an evaluation of the skin quality and medication status of the patient. Because of potential cardiac arrhythmias, peeling must be performed in a medically supervised environment, with continuous cardiac monitoring. The local complications of peeling include pigmentation changes, scarring, milia, ectropion, infection, activation of herpes simplex, and toxic shock syndrome.
面部皮肤化学剥脱术已成为面部美容外科医生的重要辅助手段。在现有的各种技术中,苯酚溶液是最常用的。剥脱会导致表皮和真皮外层产生可控的部分厚度化学灼伤。有多种技术可用于“微调”剥脱深度。剥脱皮肤的再生会产生新鲜、有序、有组织的表皮。在真皮层,表皮与下方受损真皮之间会形成一条新的2至3毫米宽的致密、紧密、有序的胶原带,这会有效消除皮肤中的细纹并减少色素沉着。这些临床和组织学变化持续时间长(15至20年),在某些患者中可能是永久性的。由于苯酚的代谢和全身并发症,患者选择应包括对肝脏、肾脏和心脏功能的全身评估,以及对患者皮肤质量和用药情况的评估。由于存在潜在的心律失常,剥脱术必须在医疗监督的环境中进行,并持续进行心脏监测。剥脱术的局部并发症包括色素沉着变化、瘢痕形成、粟丘疹、睑外翻、感染、单纯疱疹激活和中毒性休克综合征。