Krasemann Thomas, Strompen Christina, Blumenberg Jasmin, Gehrmann Josef, Burkhardtsmaier Gerhard, Vogt Johannes
Department of Pediatric Cardiology, University Children's Hospital Muenster, Albert-Schweitzer-Str. 33, D-48149 Muenster, Germany.
Eur Heart J. 2009 Jan;30(2):202-8. doi: 10.1093/eurheartj/ehn452. Epub 2008 Oct 2.
The study was designed to detect changes in corrected QT intervals over day and night in both sexes in healthy children.
The corrected QT interval was calculated from 24 h ECGs obtained from 282 healthy children aged 6 months to 18 years. The QTc interval as measured by the 24 h recording differs to the standard ECG measurement which is in average of 40-50 ms shorter. The QTc interval changes little over a 24 h period and is remarkably constant despite significant heart rate changes in healthy children.
The routine ECG-even if the calculated values differ markedly from those obtained over 24 h-seems to be a good screening method for the measurement of corrected QT intervals, because the corrected QT interval is kept constant over the whole day in healthy children.
本研究旨在检测健康儿童男女昼夜校正QT间期的变化。
从282名年龄在6个月至18岁的健康儿童中获取24小时心电图，计算校正QT间期。24小时记录测得的QTc间期与标准心电图测量值不同，平均短40 - 50毫秒。QTc间期在24小时内变化很小，尽管健康儿童心率有显著变化，但仍非常稳定。
常规心电图——即使计算值与24小时测量值有显著差异——似乎仍是测量校正QT间期的良好筛查方法，因为健康儿童的校正QT间期在一整天内保持恒定。
