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犬促肾上腺皮质激素依赖性肾上腺皮质功能亢进症的计算机断层扫描肾上腺定量分析

Computed tomographic adrenal gland quantification in canine adrenocorticotroph hormone-dependent hyperadrenocorticism.

作者信息

Bertolini Giovanna, Furlanello Tommaso, Drigo Michele, Caldin Marco

机构信息

San Marco Private Veterinary Clinic, Via Sorio 114/c, 35141 Padua, Italy.

出版信息

Vet Radiol Ultrasound. 2008 Sep-Oct;49(5):449-53. doi: 10.1111/j.1740-8261.2008.00405.x.

DOI:10.1111/j.1740-8261.2008.00405.x
PMID:18833952
Abstract

We conducted a retrospective study to determine whether multidetector computed tomography (CT) could be of value for adrenal gland assessment in dogs with pituitary-dependent hyperadrenocorticism. Adrenal gland attenuation and volume values of 49 dogs with hyperadrenocorticism were recorded and age, body weight, and gender were examined to determine if a relationship existed between these variables and adrenal gland morphology. There was not a statistically significant difference in mean X-ray attenuation of the left vs. right adrenal gland in normal dogs (35.3 +/- 6.1 HU), or in dogs with hyperadrenocorticism. The mean adrenal X-ray attenuation (+/- standard deviation [SD]) in dogs with microadenoma was 33.1 +/- 6.8 vs. 31.8 +/- 12.7 HU for dogs with macroadenoma, and these values were not statistically different. The mean volume of the left adrenal gland in normal dogs (0.59 +/- 0.17 cm3) was greater than that of the right adrenal gland (0.54 +/- 0.19 cm3) (P < 0.05). The mean CT volume (+/- SD) of the adrenal glands in dogs with microadenoma vs. macroadenoma were 1.60 +/- 1.25 vs. 2.88 +/- 1.60 cm3, respectively. There was no effect of age or gender on adrenal gland morphology or X-ray attenuation. The weight effect was the most important source of variation for the volume measurement in dogs with hyperadrenocorticism.

摘要

我们进行了一项回顾性研究,以确定多排螺旋计算机断层扫描(CT)对垂体依赖性肾上腺皮质功能亢进犬肾上腺评估是否有价值。记录了49只肾上腺皮质功能亢进犬的肾上腺衰减和体积值,并检查了年龄、体重和性别,以确定这些变量与肾上腺形态之间是否存在关联。正常犬左右肾上腺的平均X线衰减值(35.3±6.1 HU)之间,以及肾上腺皮质功能亢进犬之间,均无统计学显著差异。微腺瘤犬的肾上腺平均X线衰减值(±标准差[SD])为33.1±6.8 HU,大腺瘤犬为31.8±12.7 HU,这些值无统计学差异。正常犬左肾上腺的平均体积(0.59±0.17 cm³)大于右肾上腺(0.54±0.19 cm³)(P<0.05)。微腺瘤犬与大腺瘤犬肾上腺的平均CT体积(±SD)分别为1.60±1.25和2.88±1.60 cm³。年龄和性别对肾上腺形态或X线衰减无影响。体重影响是肾上腺皮质功能亢进犬体积测量最重要的变异来源。

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Computed tomographic adrenal gland quantification in canine adrenocorticotroph hormone-dependent hyperadrenocorticism.犬促肾上腺皮质激素依赖性肾上腺皮质功能亢进症的计算机断层扫描肾上腺定量分析
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