Ascani G, Messi M, Balercia P
Azienda Ospedaliero-Universitaria Ospedale Riuniti, Ancona, Unità Operativa di Chirurgia Maxillo-Facciale.
G Chir. 2008 Aug-Sep;29(8-9):343-6.
Pleomorphic adenoma is a benign epithelial tumour of adenoid structure preferentially arising from the parotid gland.
To analyse the outcome of patients with pleomorphic adenoma from salivary glands in order to evaluate the surgical strategy.
This is an audit of a 15-year period where 347 pleomorphic adenomas of the salivary glands were treated by the authors. Data was collected and reviewed from the records of all the patients in order to analyze gender, age, site, operative procedure, postoperative complications and recurrences.
The pleomorphic adenoma preferentially originated in the parotid gland (89.1%), and rarely in other glands. The tumour occurred more often in females than in males (F:M=1.5). Average age was 43.43 years. Pericapsular enucleation of parotid neoplasms was the commonest operation performed. Other procedures were: superficial parotidectomy, total conservative parotidectomy, submandibular total sialoadenectomy and radical surgery for lesions of the palate. Postoperative complication was temporary facial weakness in 18 patients; 2 patients developed the Frey's syndrome. No recurrences were developed in follow-up period (25-177 months).
The epidemiological aspects of pleomorphic adenoma of salivary glands retrieved in our study are similar to those reported in literature; moreover this study demonstrates that pericapsular enucleation is a viable alternative to superficial parotidectomy for the majority of parotid localizations, associated with reduced morbidity without oncological compromise.
多形性腺瘤是一种具有腺样结构的良性上皮性肿瘤,好发于腮腺。
分析涎腺多形性腺瘤患者的治疗结果,以评估手术策略。
这是一项为期15年的审计,作者对347例涎腺多形性腺瘤患者进行了治疗。从所有患者的记录中收集并审查数据,以分析性别、年龄、部位、手术方式、术后并发症和复发情况。
多形性腺瘤好发于腮腺(89.1%),很少发生于其他腺体。女性发病多于男性(女:男=1.5)。平均年龄为43.43岁。腮腺肿瘤的包膜外摘除术是最常见的手术方式。其他手术方式包括:腮腺浅叶切除术、腮腺全保守切除术、下颌下腺全涎腺切除术以及腭部病变的根治性手术。术后并发症为18例患者出现暂时性面部无力;2例患者出现味觉出汗综合征。随访期间(25 - 177个月)无复发。
我们研究中检索到的涎腺多形性腺瘤的流行病学特征与文献报道相似;此外,本研究表明,对于大多数腮腺部位的肿瘤,包膜外摘除术是腮腺浅叶切除术的可行替代方法,其发病率降低且不影响肿瘤学效果。