Taban Mehran, Sharma Sumit, Ventura Alexandre A C M, Kaiser Peter K
Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Am J Ophthalmol. 2009 Jan;147(1):101-107.e1. doi: 10.1016/j.ajo.2008.07.046. Epub 2008 Oct 4.
To investigate the in vivo real-time wound morphology of fresh 23-gauge sutureless oblique sclerotomy wounds with anterior segment optical coherence tomography (OCT).
Prospective, observational case series.
Subjects underwent three-port pars plana vitrectomy with a 23-gauge trocar/cannula microincision surgical system at the Cole Eye Institute. All incisions were created in an oblique (aka beveled or angled) fashion. The incisions were imaged with the Visante OCT (Carl Zeiss Meditec, Dublin, California, USA) device on postoperative days 1 and 8. The main outcome measure was wound structure (eg, presence of gaping) as evaluated with OCT. Surgical and ocular parameters were also recorded.
Fourteen patients were investigated. Gross clinical examination revealed no evidence of leakage. OCT demonstrated closed wounds in all eyes on postoperative days 1 and 8. The external (entry) site of the incision was occasionally seen as a gape; however the rest of the wound was closed. One patient with closed wounds had transient hypotony along with shallow peripheral choroidals noted on postoperative day 1, which resolved on their own.
Oblique incisions have been proposed for microincision sutureless vitrectomy to prevent wound leakage, hypotony, and the secondary risk of endophthalmitis. This study demonstrates that oblique incisions provide adequate wound apposition as shown by OCT even on postoperative day 1.
采用眼前节光学相干断层扫描(OCT)研究新鲜23G无缝合斜行巩膜切开伤口的体内实时伤口形态。
前瞻性观察病例系列。
在科尔眼科研究所,受试者接受了使用23G套管针/插管微切口手术系统的三通道平坦部玻璃体切除术。所有切口均以斜行(即斜面或有角度)方式制作。在术后第1天和第8天,使用Visante OCT(卡尔蔡司医疗技术公司,美国加利福尼亚州都柏林)设备对切口进行成像。主要观察指标是通过OCT评估的伤口结构(如是否存在裂开)。还记录了手术和眼部参数。
对14例患者进行了研究。大体临床检查未发现渗漏迹象。OCT显示所有眼睛在术后第1天和第8天伤口均闭合。切口的外部(入口)部位偶尔可见裂开;然而伤口的其余部分是闭合的。一名伤口闭合的患者在术后第1天出现短暂性低眼压,伴有周边脉络膜浅脱离,随后自行缓解。
有人提出采用斜行切口进行微切口无缝合玻璃体切除术,以防止伤口渗漏、低眼压和眼内炎的继发风险。本研究表明,即使在术后第1天,斜行切口也能如OCT所示提供足够的伤口对合。