Hunt Ruskin H, Thomas Kathleen M
Institute of Child Development, 51 East River Road, University of Minnesota, Minneapolis, MN 55455, USA.
Dev Psychopathol. 2008 Fall;20(4):1029-51. doi: 10.1017/S0954579408000497.
Structural and functional magnetic resonance imaging (MRI) are increasingly common research methods among investigators interested in typically and atypically developing populations. However, the effective use of these tools requires an understanding of the basis of the magnetic resonance signal, as well as some of the additional experimental complications that arise when collecting MRI data from developmental populations. This primer provides a foundation for investigators who wish to utilize MRI methods in their research and whose primary interest involves typically and atypically developing populations. The basic concepts of MRI physics are introduced, as well as the typical MRI scanner components and their role in MRI data acquisition. In addition, a variety of scan types (structural, functional, diffusion tensor) are discussed, along with a number of important experimental design factors that can impact the quality and utility of the data collected. Special consideration is given to working with pediatric and special populations.
结构和功能磁共振成像（MRI）在关注正常和异常发育人群的研究人员中越来越普遍。然而，有效使用这些工具需要了解磁共振信号的基础，以及从发育人群中收集MRI数据时出现的一些其他实验复杂性。本入门指南为希望在研究中使用MRI方法且主要关注正常和异常发育人群的研究人员提供了基础。介绍了MRI物理的基本概念，以及典型的MRI扫描仪组件及其在MRI数据采集中的作用。此外，还讨论了各种扫描类型（结构、功能、扩散张量），以及一些可能影响所收集数据质量和效用的重要实验设计因素。特别考虑了与儿科和特殊人群合作的情况。
