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瑞典儿科重症监护后的即时及5年累积结局

Immediate and 5-year cumulative outcome after paediatric intensive care in Sweden.

作者信息

Gullberg N, Kalzén H, Luhr O, Göthberg S, Winsö O, Markström A, Olsson A-K, Frostell C

机构信息

Department of Paediatric Anaesthesia and Intensive Care, Karolinska Institutet, Astrid Lindgren Children's Hospital, Stockholm, Sweden.

出版信息

Acta Anaesthesiol Scand. 2008 Sep;52(8):1086-95. doi: 10.1111/j.1399-6576.2008.01711.x.

Abstract

BACKGROUND

Little has been reported about intensive care of children in Sweden. The aims of this study are to (I) assess the number of admissions, types of diagnoses and length-of-stay (LOS) for all Swedish children admitted to intensive care during the years 1998-2001, and compare paediatric intensive care units (PICUs) with other intensive care units (adult ICUs) (II) assess immediate (ICU) and cumulative 5-year mortality and (III) determine the actual consumption of paediatric intensive care for the defined age group in Sweden.

METHODS

Children between 6 months and 16 years of age admitted to intensive care in Sweden were included in a national multicentre, ambidirectional cohort study. In PICUs, data were also collected for infants aged 1-6 months. Survival data were retrieved from the National Files of Registration, 5 years after admission.

RESULTS

Eight-thousand sixty-three admissions for a total of 6661 patients were identified, corresponding to an admission rate of 1.59/1000 children per year. Median LOS was 1 day. ICU mortality was 2.1% and cumulative 5-year mortality rate was 5.6%. Forty-four per cent of all admissions were to a PICU.

CONCLUSIONS

This study has shown that Sweden has a low immediate ICU mortality, similar in adult ICU and PICU. Patients discharged alive from an ICU had a 20-fold increased mortality risk, compared with a control cohort for the 5-year period. Less than half of the paediatric patients admitted for intensive care in Sweden were cared for in a PICU. Studies are needed to evaluate whether a centralization of paediatric intensive care in Sweden would be beneficial to the paediatric population.

摘要

背景

瑞典关于儿童重症监护的报道较少。本研究的目的是:(I)评估1998 - 2001年期间瑞典所有入住重症监护病房的儿童的入院人数、诊断类型和住院时间(LOS),并比较儿科重症监护病房(PICU)与其他重症监护病房(成人ICU);(II)评估即刻(ICU)和累积5年死亡率;(III)确定瑞典特定年龄组儿童重症监护的实际消耗量。

方法

纳入瑞典6个月至16岁入住重症监护病房的儿童,进行全国多中心双向队列研究。在PICU中,还收集了1 - 6个月婴儿的数据。入院5年后从国家登记档案中获取生存数据。

结果

共识别出8063例入院病例,涉及6661名患者,对应年入院率为1.59/1000名儿童。中位住院时间为1天。ICU死亡率为2.1%,累积5年死亡率为5.6%。所有入院病例中44%入住PICU。

结论

本研究表明,瑞典即刻ICU死亡率较低,成人ICU和PICU相似。与对照组相比,从ICU存活出院的患者在5年期间死亡风险增加了20倍。在瑞典,接受重症监护的儿科患者中不到一半在PICU接受治疗。需要开展研究来评估瑞典儿科重症监护的集中化是否对儿科人群有益。

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