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首例起源于输卵管的脂肪肉瘤:病例报告及文献复习

First case of liposarcoma arising from the fallopian tube: case report and review of the literature.

作者信息

Oishi Hitomi, Moriyama Shingo, Kotera Kouhei, Miura Kiyonori, Masuzaki Hideaki

机构信息

Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.

出版信息

J Obstet Gynaecol Res. 2008 Aug;34(4 Pt 2):713-6. doi: 10.1111/j.1447-0756.2008.00913.x.

Abstract

Liposarcoma is the most common soft tissue sarcoma in adults, and it typically occurs in either the retroperitoneum or the extremities. However, this malignant tumor is very rare in the female reproductive system. A 58-year-old woman presented with acute abdominal pain, and computed tomography (CT) scan detected multiple masses measuring 4-6 cm in size with a fatty density in her adnexal region. Laparoscopic evaluation revealed tumors of the left fallopian tube with a normal left ovary. Histopathological evaluation of the resected pelvic tumors showed lipocytes and lipoblasts of various sizes, leading to diagnosis of well-differentiated liposarcoma of the left adnexal region. This is the first known case of a liposarcoma arising from the fallopian tube. When a pelvic mass with fatty density that does not show typical findings of a mature cystic teratoma is detected by either CT or magnetic resonance imaging, the possibility of a liposarcoma should be considered.

摘要

脂肪肉瘤是成人最常见的软组织肉瘤,通常发生于腹膜后或四肢。然而,这种恶性肿瘤在女性生殖系统中非常罕见。一名58岁女性因急性腹痛就诊,计算机断层扫描(CT)发现其附件区有多个大小为4 - 6厘米、密度似脂肪的肿块。腹腔镜检查发现左侧输卵管有肿瘤,左侧卵巢正常。对切除的盆腔肿瘤进行组织病理学评估显示有大小各异的脂肪细胞和成脂细胞,从而诊断为左侧附件区高分化脂肪肉瘤。这是首例已知的起源于输卵管的脂肪肉瘤病例。当通过CT或磁共振成像检测到盆腔内有密度似脂肪且不具有成熟囊性畸胎瘤典型表现的肿块时,应考虑脂肪肉瘤的可能性。

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