Ingec Metin, Kadanali Sedat, Erdogan Fazi
Departments of Obstetrics and Gynecology and of Pathology, University of Ataturk, Erzurum, Turkey.
J Reprod Med. 2007 Mar;52(3):247-9.
Primary mature solid teratomas of the fallopian tube are extremely rare and only 11 cases have been reported in the literature. A woman presented with a mature, solid teratoma of the fallopian tube, possibly the largest solid teratoma on record.
A 24-year-old, nulliparous woman presented with abdominal distention, intermittent abdominal pain, nausea and vomiting for 4 weeks and was admitted to the hospital. Abdominal examination revealed a palpable, nontender mass. Computed tomography showed a hypodense lesion in the abdomen. Serum concentrations of carcinoembryonic antigen (2.6 ng/mL) and beta-human chorionic gonadotropin (0.1 mIU/mL) were within normal limits, while serum levels of CA-125 (130 U/mL) and CA-19.9 (237 U/mL) were elevated. A multilobulated, pedunculated, mature, solid teratoma of the fallopian tube measured 31 x 21 x 14 cm and weighed 2,400 g. At laparotomy, it was located in the fimbrial portion of the left fallopian tube, and a left salpingectomy was performed. The tumor consisted of bone, hair, and sebaceous and sweat glands. The cavity of the cyst was lined mainly with skin composed of keratinized squamous epithelium and contained abundant sebaceous and sweat glands.
In cases of undetermined pelvic or abdominal masses, especially with calcification, a teratoma of the fallopian tube should be considered.
原发性成熟型输卵管实性畸胎瘤极为罕见，文献中仅报道过11例。一名女性患者出现了输卵管成熟实性畸胎瘤，可能是有记录以来最大的实性畸胎瘤。
一名24岁未生育女性因腹胀、间歇性腹痛、恶心和呕吐4周入院。腹部检查发现可触及一个无压痛的肿块。计算机断层扫描显示腹部有一个低密度病变。癌胚抗原（2.6 ng/mL）和β-人绒毛膜促性腺激素（0.1 mIU/mL）血清浓度在正常范围内，而CA-125（130 U/mL）和CA-19.9（237 U/mL）血清水平升高。一个多叶、带蒂、成熟的输卵管实性畸胎瘤大小为31×21×14 cm，重2400 g。剖腹手术时，肿瘤位于左侧输卵管伞端，遂行左侧输卵管切除术。肿瘤由骨、毛发、皮脂腺和汗腺组成。囊肿腔内主要衬以由角化鳞状上皮构成的皮肤，含有丰富的皮脂腺和汗腺。
对于盆腔或腹部肿块性质不明的病例，尤其是伴有钙化的情况，应考虑输卵管畸胎瘤。
