Cheung C M, Tsoi T H, Hon Sonny F K, Au-Yeung M, Shiu K L, Lee C N, Huang C Y
Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.
Hong Kong Med J. 2008 Oct;14(5):367-70.
To investigate whether the National Institutes of Health Stroke Scale (NIHSS) can be used to predict mortality and functional outcome in patients presenting with intracerebral haemorrhage.
Retrospective study of a prospectively collected cohort.
Regional hospital, Hong Kong.
A cohort of 359 patients presented to our hospital from 1996 to 2001 with their first-ever stroke and intracerebral haemorrhage.
The sensitivity and specificity of the NIHSS with a cut-off point of 20 in predicting mortality at 30 days and 5 years, and a favourable functional outcome at 5 years.
A total of 359 patients were available for analysis and were divided into three subgroups according to the site and the size of the haematoma. The NIHSS can predict 30-day mortality with a sensitivity of 81% [corrected] and a specificity of 90% [corrected] The NIHSS can predict 5-year mortality with a sensitivity of 57% [corrected] and a specificity of 92% [corrected] In predicting favourable functional outcomes at 5 years, the NIHSS had a sensitivity of 98% [corrected] and a specificity of 16% [corrected]
The NIHSS performed on admission can be used to predict mortality at 30 days and 5 years as well as favourable functional outcome at 5 years, all with an acceptable sensitivity and specificity.
研究美国国立卫生研究院卒中量表(NIHSS)是否可用于预测脑出血患者的死亡率和功能转归。
对前瞻性收集的队列进行回顾性研究。
香港地区医院。
1996年至2001年期间首次因卒中及脑出血就诊于我院的359例患者。
以20分为界值的NIHSS在预测30天和5年死亡率以及5年良好功能转归方面的敏感性和特异性。
共有359例患者可供分析,并根据血肿部位和大小分为三个亚组。NIHSS预测30天死亡率的敏感性为81%[校正后],特异性为90%[校正后];NIHSS预测5年死亡率的敏感性为57%[校正后],特异性为92%[校正后]。在预测5年良好功能转归方面,NIHSS的敏感性为98%[校正后],特异性为16%[校正后]。
入院时进行的NIHSS可用于预测30天和5年死亡率以及5年良好功能转归,且敏感性和特异性均可接受。