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使用美国国立卫生研究院卒中量表(NIHSS)预测脑出血患者的死亡率和预后。

Using the National Institutes of Health Stroke Scale (NIHSS) to predict the mortality and outcome of patients with intracerebral haemorrhage.

作者信息

Cheung C M, Tsoi T H, Hon Sonny F K, Au-Yeung M, Shiu K L, Lee C N, Huang C Y

机构信息

Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.

出版信息

Hong Kong Med J. 2008 Oct;14(5):367-70.

Abstract

OBJECTIVES

To investigate whether the National Institutes of Health Stroke Scale (NIHSS) can be used to predict mortality and functional outcome in patients presenting with intracerebral haemorrhage.

DESIGN

Retrospective study of a prospectively collected cohort.

SETTING

Regional hospital, Hong Kong.

PATIENTS

A cohort of 359 patients presented to our hospital from 1996 to 2001 with their first-ever stroke and intracerebral haemorrhage.

MAIN OUTCOME MEASURES

The sensitivity and specificity of the NIHSS with a cut-off point of 20 in predicting mortality at 30 days and 5 years, and a favourable functional outcome at 5 years.

RESULTS

A total of 359 patients were available for analysis and were divided into three subgroups according to the site and the size of the haematoma. The NIHSS can predict 30-day mortality with a sensitivity of 81% [corrected] and a specificity of 90% [corrected] The NIHSS can predict 5-year mortality with a sensitivity of 57% [corrected] and a specificity of 92% [corrected] In predicting favourable functional outcomes at 5 years, the NIHSS had a sensitivity of 98% [corrected] and a specificity of 16% [corrected]

CONCLUSIONS

The NIHSS performed on admission can be used to predict mortality at 30 days and 5 years as well as favourable functional outcome at 5 years, all with an acceptable sensitivity and specificity.

摘要

目的

研究美国国立卫生研究院卒中量表(NIHSS)是否可用于预测脑出血患者的死亡率和功能转归。

设计

对前瞻性收集的队列进行回顾性研究。

地点

香港地区医院。

患者

1996年至2001年期间首次因卒中及脑出血就诊于我院的359例患者。

主要观察指标

以20分为界值的NIHSS在预测30天和5年死亡率以及5年良好功能转归方面的敏感性和特异性。

结果

共有359例患者可供分析,并根据血肿部位和大小分为三个亚组。NIHSS预测30天死亡率的敏感性为81%[校正后],特异性为90%[校正后];NIHSS预测5年死亡率的敏感性为57%[校正后],特异性为92%[校正后]。在预测5年良好功能转归方面,NIHSS的敏感性为98%[校正后],特异性为16%[校正后]。

结论

入院时进行的NIHSS可用于预测30天和5年死亡率以及5年良好功能转归,且敏感性和特异性均可接受。

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