Ganzini Linda, Goy Elizabeth R, Dobscha Steven K
Columbia Center for the Study of Chronic, Comorbid Mental and Physical Disorders, Health Services Research and Development, Portland Veterans Affairs Medical Center, PO Box 1034, Portland, OR 97239, USA.
BMJ. 2008 Oct 7;337:a1682. doi: 10.1136/bmj.a1682.
To determine the prevalence of depression and anxiety in terminally ill patients pursuing aid in dying from physicians.
Cross sectional survey.
State of Oregon, USA.
58 Oregonians, most terminally ill with cancer or amyotrophic lateral sclerosis, who had either requested aid in dying from a physician or contacted an aid in dying advocacy organisation.
Diagnosis of depression or anxiety according to the hospital anxiety and depression scale and the structured clinical interview for the Diagnostic and Statistical Manual of Mental Disorders.
15 study participants met "caseness" criteria for depression, and 13 met criteria for anxiety. 42 patients died by the end of the study; 18 received a prescription for a lethal drug under the Death with Dignity Act, and nine died by lethal ingestion. 15 participants who received a prescription for a lethal drug did not meet criteria for depression; three did. All three depressed participants died by legal ingestion within two months of the research interview.
Although most terminally ill Oregonians who receive aid in dying do not have depressive disorders, the current practice of the Death with Dignity Act may fail to protect some patients whose choices are influenced by depression from receiving a prescription for a lethal drug.
确定寻求医生协助死亡的晚期患者中抑郁症和焦虑症的患病率。
横断面调查。
美国俄勒冈州。
58名俄勒冈人,大多数患有晚期癌症或肌萎缩侧索硬化症,他们要么已请求医生协助死亡,要么联系过协助死亡倡导组织。
根据医院焦虑抑郁量表以及《精神疾病诊断与统计手册》的结构化临床访谈对抑郁症或焦虑症进行诊断。
15名研究参与者符合抑郁症的“病例”标准,13名符合焦虑症标准。到研究结束时,42名患者死亡;18人根据《尊严死亡法案》获得了致命药物处方,9人通过服用致命药物死亡。15名获得致命药物处方的参与者不符合抑郁症标准;3人符合。所有三名患有抑郁症的参与者在研究访谈后的两个月内通过合法服药死亡。
尽管大多数在俄勒冈州接受协助死亡的晚期患者没有抑郁症,但《尊严死亡法案》目前的实施可能无法保护一些因抑郁症影响其选择的患者不被开具致命药物处方。