McInnes Elizabeth, Bell-Syer Sally Em, Dumville Jo C, Legood Rosa, Cullum Nicky A
Cochrane Database Syst Rev. 2008 Oct 8(4):CD001735. doi: 10.1002/14651858.CD001735.pub3.
Pressure ulcers (also known as bedsores, pressure sores, decubitus ulcers) are areas of localised damage to the skin and underlying tissue due to pressure, shear or friction. They are common in the elderly and immobile and costly in financial and human terms. Pressure-relieving beds, mattresses and seat cushions are widely used as aids to prevention in both institutional and non-institutional settings.
This systematic review seeks to answer the following questions:(1) to what extent do pressure-relieving cushions, beds, mattress overlays and mattress replacements reduce the incidence of pressure ulcers compared with standard support surfaces?(2) how effective are different pressure-relieving surfaces in preventing pressure ulcers, compared to one another?
For this second update the Cochrane Wounds Group Specialised Register was searched (28/2/08), The Cochrane Central Register of Controlled Trials (CENTRAL)(2008 Issue 1), Ovid MEDLINE (1950 to February Week 3 2008), Ovid EMBASE (1980 to 2008 Week 08) and Ovid CINAHL (1982 to February Week 3 2008). The reference sections of included studies were searched for further trials.
Randomised controlled trials (RCTs), published or unpublished, which assessed the effectiveness of beds, mattresses, mattress overlays, and seating cushions for the prevention of pressure ulcers, in any patient group, in any setting. Study selection was undertaken by at least two authors independently with a third author resolving uncertainty. RCTs were eligible for inclusion if they reported an objective, clinical outcome measure such as incidence and severity of new of pressure ulcers developed. Studies which only reported proxy outcome measures such as interface pressure were excluded.
Trial data were extracted by one researcher and checked by a second. The results from each study are presented as relative risk for dichotomous variables. Where deemed appropriate, similar studies were pooled in a meta analysis.
For this second update 11 trials met the inclusion criteria bringing the total number of RCTs included in the review to 52.Foam alternatives to the standard hospital foam mattress can reduce the incidence of pressure ulcers in people at risk. The relative merits of alternating and constant low pressure devices are unclear. There is one high quality trial comparing the different alternating pressure devices for pressure ulcer prevention which suggests that alternating pressure mattresses may be more cost effective than alternating pressure overlays.Pressure-relieving overlays on the operating table have been shown to reduce postoperative pressure ulcer incidence, although two studies indicated that foam overlays resulted in adverse skin changes. Two trials indicated that Australian standard medical sheepskins prevented pressure ulcers. There is insufficient evidence to draw conclusions on the value of seat cushions, limb protectors and various constant low pressure devices as pressure ulcer prevention strategies.A study of Accident & Emergency trolley overlays did not identify a reduction in pressure ulcer incidence. There are tentative indications that foot waffle heel elevators, a particular low air loss hydrotherapy mattress and two types of operating theatre overlays are harmful.
AUTHORS' CONCLUSIONS: In people at high risk of pressure ulcer development higher specification foam mattresses rather than standard hospital foam mattresses should be used. The relative merits of higher-tech constant low pressure and alternating pressure for prevention are unclear but alternating pressure mattresses may be more cost effective than alternating pressure overlays. Medical grade sheepskins are associated with a decrease in pressure ulcer development. Organisations might consider the use of some forms of pressure relief for high risk patients in the operating theatre. Seat cushions and overlays designed for use in Accident & Emergency settings have not been adequately evaluated.
压疮(也称为褥疮、压力性溃疡、压疮溃疡)是由于压力、剪切力或摩擦力导致皮肤和皮下组织局部受损的区域。它们在老年人和行动不便者中很常见,在经济和人力方面成本高昂。减压床、床垫和座垫在机构和非机构环境中都被广泛用作预防辅助工具。
本系统评价旨在回答以下问题:(1)与标准支撑面相比,减压座垫、床、床垫罩和床垫更换装置在多大程度上降低了压疮的发生率?(2)与彼此相比,不同的减压表面在预防压疮方面的效果如何?
对于本次第二次更新,检索了Cochrane伤口小组专门注册库(2008年2月28日)、Cochrane对照试验中心注册库(CENTRAL)(2008年第1期)、Ovid MEDLINE(1950年至2008年第3周)、Ovid EMBASE(1980年至2008年第8周)和Ovid CINAHL(1982年至2008年第3周)。对纳入研究的参考文献部分进行检索以查找更多试验。
随机对照试验(RCT),无论已发表或未发表,评估床、床垫、床垫罩和座垫在任何患者群体、任何环境中预防压疮的有效性。研究选择由至少两名作者独立进行,第三名作者解决不确定性问题。如果RCT报告了客观的临床结局指标,如新发压疮的发生率和严重程度,则有资格纳入。仅报告替代结局指标(如界面压力)的研究被排除在外。
试验数据由一名研究人员提取,另一名研究人员进行核对。每项研究的结果以二分类变量的相对风险表示。在认为合适的情况下,将相似的研究汇总进行荟萃分析。
对于本次第二次更新,有11项试验符合纳入标准,使本评价纳入的RCT总数达到52项。标准医院泡沫床垫的泡沫替代品可降低高危人群压疮的发生率。交替式和持续低压装置的相对优点尚不清楚。有一项高质量试验比较了不同的交替压力装置预防压疮的效果,表明交替压力床垫可能比交替压力床垫罩更具成本效益。手术台上的减压床垫罩已被证明可降低术后压疮的发生率,尽管两项研究表明泡沫床垫罩会导致皮肤不良变化。两项试验表明,澳大利亚标准医用羊皮可预防压疮。没有足够的证据就座垫、肢体保护器和各种持续低压装置作为压疮预防策略的价值得出结论。一项关于急诊推车床垫罩的研究未发现压疮发生率降低。初步迹象表明,脚型华夫脚跟抬高器、一种特殊的低气耗水疗床垫和两种手术室床垫罩是有害的。
对于压疮发生风险高的人群,应使用规格更高的泡沫床垫而非标准医院泡沫床垫。高科技持续低压和交替压力预防的相对优点尚不清楚,但交替压力床垫可能比交替压力床垫罩更具成本效益。医用级羊皮与压疮发生率降低有关。各机构可能应考虑为手术室中的高危患者采用某种形式的减压措施。为急诊环境设计的座垫和床垫罩尚未得到充分评估。