McInnes Elizabeth, Jammali-Blasi Asmara, Bell-Syer Sally Em, Dumville Jo C, Cullum Nicky
Nursing Research Institute, St Vincent's and Mater Health Sydney ACU, National Centre for Clinical Outcomes Research (NaCCOR), Nursing and Midwifery, Australia, Research Room, Level 5 DeLacy Building, St Vincent's Hospital, Victoria Street, Darlinghurst, New South Wales, Australia, 2010.
Cochrane Database Syst Rev. 2011 Apr 13(4):CD001735. doi: 10.1002/14651858.CD001735.pub4.
Pressure ulcers (i.e. bedsores, pressure sores, decubitus ulcers) are areas of localised damage to the skin and underlying tissue. They are common in the elderly and immobile, and costly in financial and human terms. Pressure-relieving support surfaces (i.e. beds, mattresses, seat cushions etc) are used to help prevent ulcer development.
This systematic review seeks to establish: (1) the extent to which pressure-relieving support surfaces reduce the incidence of pressure ulcers compared with standard support surfaces, and, (2) their comparative effectiveness in ulcer prevention.
For this third update we searched: the Cochrane Wounds Group Specialised Register (searched 8 December 2010), The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, Issue 4); Ovid MEDLINE (1950 to November Week 3 2010); Ovid MEDLINE (In-Process & Other Non-Indexed Citations December 07, 2010); Ovid EMBASE (1980 to 2010 Week 48); EBSCO CINAHL (1982 to 3 December 2010), and the reference sections of included studies.
Randomised controlled trials (RCTs) and quasi-randomised studies, published or unpublished, that assessed the effects of any support surface for prevention of pressure ulcers, in any patient group or setting which measured pressure ulcer incidence.Studies reporting only proxy outcomes (e.g. interface pressure) were excluded. Two review authors independently selected studies.
Data were extracted by one author and checked by another. Where appropriate, estimates from similar studies were pooled for meta-analysis.
One new trial was included, bringing the total of included studies to 53.Foam alternatives to standard hospital foam mattresses reduce the incidence of pressure ulcers in people at risk (RR 0.40 95% CI 0.21 to 0.74). The relative merits of alternating- and constant low-pressure devices are unclear. One high-quality trial suggested that alternating-pressure mattresses may be more cost effective than alternating-pressure overlays in a UK context.Pressure-relieving overlays on the operating table reduce postoperative pressure ulcer incidence, although two studies indicated that foam overlays caused adverse skin changes. Meta-analysis of three trials indicated that Australian standard medical sheepskins prevent pressure ulcers (RR 0.56 95% CI 0.32 to 0.97).
AUTHORS' CONCLUSIONS: People at high risk of developing pressure ulcers should use higher-specification foam mattresses rather than standard hospital foam mattresses. The relative merits of higher-specification constant low-pressure and alternating-pressure support surfaces for preventing pressure ulcers are unclear, but alternating-pressure mattresses may be more cost effective than alternating-pressure overlays in a UK context. Medical grade sheepskins are associated with a decrease in pressure ulcer development. Organisations might consider the use of some forms of pressure relief for high risk patients in the operating theatre.
压疮(即褥疮、压力性溃疡、压疮性溃疡)是皮肤及皮下组织的局部损伤区域。在老年人和行动不便者中较为常见,在经济和人力方面成本高昂。减压支撑面(如床、床垫、座垫等)用于帮助预防溃疡的发生。
本系统评价旨在确定:(1)与标准支撑面相比,减压支撑面在多大程度上降低了压疮的发生率,以及(2)它们在预防溃疡方面的相对有效性。
对于本次第三次更新,我们检索了:Cochrane伤口小组专业注册库(2010年12月8日检索)、Cochrane对照试验中心注册库(CENTRAL)(《Cochrane图书馆》2010年第4期);Ovid MEDLINE(1950年至2010年11月第3周);Ovid MEDLINE(在研及其他未索引引文,2010年12月7日);Ovid EMBASE(1980年至2010年第48周);EBSCO CINAHL(1982年至2010年12月3日),以及纳入研究的参考文献部分。
评估任何支撑面预防压疮效果的随机对照试验(RCT)和半随机研究,无论已发表或未发表,涉及任何患者群体或测量压疮发生率的环境。仅报告替代结局(如界面压力)的研究被排除。两位综述作者独立选择研究。
数据由一位作者提取,另一位作者进行核对。在适当情况下,将类似研究的估计值合并进行荟萃分析。
纳入了一项新试验,使纳入研究总数达到53项。标准医院泡沫床垫的泡沫替代品可降低高危人群压疮的发生率(相对危险度0.40,95%可信区间0.21至0.74)。交替式和持续低压装置的相对优点尚不清楚。一项高质量试验表明,在英国,交替压力床垫可能比交替压力覆盖物更具成本效益。手术台上的减压覆盖物可降低术后压疮的发生率,尽管两项研究表明泡沫覆盖物会引起皮肤不良反应。三项试验的荟萃分析表明,澳大利亚标准医用羊皮可预防压疮(相对危险度0.56,95%可信区间0.32至0.97)。
发生压疮高危人群应使用更高规格的泡沫床垫,而非标准医院泡沫床垫。更高规格的持续低压和交替压力支撑面在预防压疮方面的相对优点尚不清楚,但在英国,交替压力床垫可能比交替压力覆盖物更具成本效益。医用级羊皮与压疮发生率降低有关。各机构可能应考虑为手术室中的高危患者采用某种形式的减压措施。