Zhang Yan-Ming, Wu De-Pei, Sun Yu-Mei, Lu Shu-Hua, Zhu Ming-Qing
Department of Hematology, Second People's Hospital of Huai'an, Huai'an 223002, China.
Zhonghua Xue Ye Xue Za Zhi. 2008 May;29(5):293-5.
To report a case of pure erythroid leukemia.
The clinical features, treatment and prognosis of a rare case of pure erythroid leukemia were reported, and the related literature was reviewed.
The pure erythroid leukemia patient was diagnosed by 90.4% pronormoblasts in bone marrow, 99.5% for erythroid antigen CD71, 67.4% for glycophorin A were detected, while no differentiation antigen of myeloid, lymphoid and megakaryocyte lineages were observed. HAG (homoharringtonine + Cytarabine and G-CSF) regimen were administered with no effect. The patient developed multiple organ failure and died soon.
Pure erythroid leukemia has a fulminant clinical course with poor response to chemotherapy and worse prognosis.
报告1例纯红细胞白血病病例。
报告1例罕见的纯红细胞白血病病例的临床特征、治疗及预后，并复习相关文献。
该纯红细胞白血病患者骨髓中早幼红细胞占90.4%，红细胞抗原CD71检测阳性率为99.5%，血型糖蛋白A检测阳性率为67.4%，未观察到髓系、淋巴系及巨核细胞系的分化抗原。采用高三尖杉酯碱+阿糖胞苷及粒细胞集落刺激因子（HAG）方案治疗无效。患者出现多器官功能衰竭，不久后死亡。
纯红细胞白血病临床过程凶险，化疗反应差，预后不良。
