Sejna I, Vydrová J, Cerná O, Kredba V, Votruba V
Otorinolaryngologická klinika ILF, Praha.
Cesk Pediatr. 1991 Jan;46(1):28-30.
The authors examined two groups of children treated during neonatal period with high doses of Gentamycin. The reasons for Gentamycin treatment at the intensive care unit were infection of the CNS, pneumopaties, intracranial haemorrhagiae, cerebral oedema and other causes. The first group of children was treated in 1981, the second one in 1986. Both groups were examined in 1987. All children were evaluated to objective hearing tests, impedance audiometry by acoustically evoked potentials of the brain stem. Children of the first group examined during their fifth or sixth year were also submitted to a hearing test. The control group was formed by children born in 1986 treated at the intensive care unit with similar indications but who were not given Gentamycin. A total of 51 children were examined. Twenty-two children examined at the age of five had no hearing impairment. Acoustically evoked potentials of the brain stem have a wide variability which may be the manifestation of the disease which led to admission to the intensive care unit. Therefore it should be conceived as a screening examination and the revealed pathological findings should be verified by repeated examinations. Possible hearing disorders should be confirmed at a later age by conventional examinations.
作者研究了两组在新生儿期接受高剂量庆大霉素治疗的儿童。在重症监护病房使用庆大霉素治疗的原因包括中枢神经系统感染、肺炎、颅内出血、脑水肿及其他原因。第一组儿童于1981年接受治疗，第二组于1986年接受治疗。两组均于1987年接受检查。所有儿童均接受客观听力测试、通过脑干听觉诱发电位进行的声阻抗测听。第一组在其五岁或六岁时接受检查的儿童也接受了听力测试。对照组由1986年在重症监护病房接受治疗、有类似指征但未使用庆大霉素的儿童组成。总共检查了51名儿童。22名五岁时接受检查的儿童没有听力障碍。脑干听觉诱发电位具有很大的变异性，这可能是导致入住重症监护病房的疾病的表现。因此，应将其视为一种筛查检查，所发现的病理结果应通过重复检查进行核实。可能存在的听力障碍应在以后的年龄通过常规检查加以确认。
