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用于治疗骶髂关节炎慢性疼痛的冷却射频系统:首例病例系列报告

Cooled radiofrequency system for the treatment of chronic pain from sacroiliitis: the first case-series.

作者信息

Kapural Leonardo, Nageeb Fady, Kapural Miranda, Cata Juan P, Narouze Samer, Mekhail Nagy

机构信息

Department of Pain Management, Cleveland Clinic, Cleveland, Ohio 44195, USA.

出版信息

Pain Pract. 2008 Sep-Oct;8(5):348-54. doi: 10.1111/j.1533-2500.2008.00231.x.

DOI:10.1111/j.1533-2500.2008.00231.x
PMID:18844853
Abstract

Sacroiliitis and sacroiliac (SI) joint dysfunction are frequent causes of the chronic lower back pain. Therapeutic solutions include intra-atricular injections with short-term pain relief and surgical fusion, which appears ineffective. Radiofrequency (RF) of the joint capsule or lateral branches has been previously reported with variable successes. Cooling tissue adjacent to the electrode (cooled RF) increases the radius of lesion. We present here the first retrospective data on pain relief and changes in function after such RF denervation. We reviewed electronic records of 27 patients with chronic low back pain (median 5 years) who underwent cooled RF of S1, S2, and S3 lateral branches and of dorsal ramus (DR) L5 following two diagnostic SI joint blocks (>50% of pain relief). Patient sample consisted of 20 women and 7 men, 38 to 92 years old. Pain disability index (PDI), visual analog scale (VAS) pain scores, global patient satisfaction (GPE) and opioid use before and 3-4 months after the procedure were analyzed. One patient had an incomplete chart. Observed were improvements in function (PDI) from 32.7 +/- 9.9 to 20.3 +/- 12.1 (P < 0.001) and VAS pain scores 7.1 +/- 1.6 to 4.2 +/- 2.5 (P < 0.001) at 3-4 months after the procedure. Opioid use decreased from median 30 to 20 mg morphine equivalent. Eighteen patients rated their improvement in pain scores using GPE as improved or much improved, while eight claimed minimal or no improvement. The majority of patients with chronic SI joint pain experienced a clinically relevant degree of pain relief and improved function following cooled RF of sacral lateral branches and DR of L5 at 3-4 months follow-up.

摘要

骶髂关节炎和骶髂(SI)关节功能障碍是慢性下腰痛的常见原因。治疗方法包括关节内注射以缓解短期疼痛和手术融合,但手术融合似乎无效。此前有报道称,对关节囊或外侧分支进行射频(RF)治疗的效果不一。冷却电极附近的组织(冷射频)可增加损伤半径。我们在此展示了关于这种射频去神经支配术后疼痛缓解和功能变化的首份回顾性数据。我们回顾了27例慢性下腰痛患者(中位病程5年)的电子病历,这些患者在两次诊断性骶髂关节阻滞(疼痛缓解>50%)后,接受了S1、S2和S3外侧分支以及L5背侧支的冷射频治疗。患者样本包括20名女性和7名男性,年龄在38至92岁之间。分析了术前和术后3 - 4个月的疼痛残疾指数(PDI)、视觉模拟量表(VAS)疼痛评分、患者总体满意度(GPE)和阿片类药物使用情况。1例患者病历不完整。术后3 - 4个月时观察到功能(PDI)从32.7±9.9改善至20.3±12.1(P < 0.001),VAS疼痛评分从7.1±1.6降至4.2±2.5(P < 0.001)。阿片类药物使用量从吗啡当量中位数30毫克降至20毫克。18名患者使用GPE将疼痛评分改善评为改善或显著改善,而8名患者称改善极小或无改善。在3 - 4个月的随访中,大多数慢性骶髂关节疼痛患者在接受骶外侧分支和L5背侧支冷射频治疗后,经历了临床上显著的疼痛缓解和功能改善。

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