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本文引用的文献

1
Analysis of genetic relatedness of Haemophilus influenzae isolates by multilocus sequence typing.通过多位点序列分型分析流感嗜血杆菌分离株的遗传相关性。
J Bacteriol. 2008 Feb;190(4):1473-83. doi: 10.1128/JB.01207-07. Epub 2007 Dec 7.
2
Relationships of nontypeable Haemophilus influenzae strains to hemolytic and nonhemolytic Haemophilus haemolyticus strains.不可分型流感嗜血杆菌菌株与溶血和非溶血溶血嗜血杆菌菌株的关系。
J Clin Microbiol. 2008 Feb;46(2):406-16. doi: 10.1128/JCM.01832-07. Epub 2007 Nov 26.
3
Pharyngeal colonization dynamics of Haemophilus influenzae and Haemophilus haemolyticus in healthy adult carriers.健康成年携带者中流感嗜血杆菌和溶血嗜血杆菌的咽部定植动态
J Clin Microbiol. 2007 Oct;45(10):3207-17. doi: 10.1128/JCM.00492-07. Epub 2007 Aug 8.
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Histidine auxotrophy in commensal and disease-causing nontypeable Haemophilus influenzae.共生和致病的不可分型流感嗜血杆菌中的组氨酸营养缺陷型
J Bacteriol. 2007 Jul;189(14):4994-5001. doi: 10.1128/JB.00146-07. Epub 2007 May 11.
5
Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae.溶血嗜血杆菌：一种需与流感嗜血杆菌相鉴别的人类呼吸道共生菌。
J Infect Dis. 2007 Jan 1;195(1):81-9. doi: 10.1086/509824. Epub 2006 Nov 27.
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Population genetics of microbial pathogens estimated from multilocus sequence typing (MLST) data.基于多位点序列分型（MLST）数据估算的微生物病原体群体遗传学。
Infect Genet Evol. 2006 Mar;6(2):97-112. doi: 10.1016/j.meegid.2005.02.003. Epub 2005 Mar 24.
7
Characterization of genetic and phenotypic diversity of invasive nontypeable Haemophilus influenzae.侵袭性非分型流感嗜血杆菌的遗传和表型多样性特征分析
Infect Immun. 2005 Sep;73(9):5853-63. doi: 10.1128/IAI.73.9.5853-5863.2005.
8
High level of sequence diversity in the 16S rRNA genes of Haemophilus influenzae isolates is useful for molecular subtyping.流感嗜血杆菌分离株16S rRNA基因的高度序列多样性有助于分子分型。
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Small change: keeping pace with microevolution.微小变化：紧跟微观进化的步伐。
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10
eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data.eBURST：从多位点序列分型数据推断相关细菌基因型簇之间的进化谱系模式。
J Bacteriol. 2004 Mar;186(5):1518-30. doi: 10.1128/JB.186.5.1518-1530.2004.

来自一家日托中心两名儿童的不可分型流感嗜血杆菌分离株具有高度遗传多样性。

High genetic diversity of nontypeable Haemophilus influenzae isolates from two children attending a day care center.

作者信息

Lacross Nathan C, Marrs Carl F, Patel Mayuri, Sandstedt Sara A, Gilsdorf Janet R

机构信息

Department of Pediatrics and Communicable Diseases, L2225 Women's Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0244, USA.

出版信息

J Clin Microbiol. 2008 Nov;46(11):3817-21. doi: 10.1128/JCM.00940-08. Epub 2008 Sep 24.

DOI:10.1128/JCM.00940-08
PMID:18845825
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2576570/
Abstract

Twenty-one nontypeable Haemophilus influenzae (NTHi) isolates from the throats of two healthy children were genotyped by multilocus sequence typing. Nine unique sequence types (STs) were identified. These STs were scattered throughout the phylogenetic tree of reported NTHi STs, demonstrating the high level of NTHi diversity found in colonized children.

摘要

对来自两名健康儿童咽喉部的21株不可分型流感嗜血杆菌（NTHi）分离株进行多位点序列分型。鉴定出9种独特的序列型（STs）。这些STs分散在已报道的NTHi STs系统发育树中，表明在定植儿童中发现的NTHi具有高度多样性。