Garstin W I, Kaufman Z, Michell M J, Baum M
Department of Surgery, Rayne Institute, King's College Hospital, London.
Clin Radiol. 1991 Aug;44(2):89-91. doi: 10.1016/s0009-9260(05)80503-3.
The cases of two poorly controlled insulin dependent diabetic women, presenting with hard discrete breast lumps clinically suspicious of carcinoma are presented. Mammography revealed dense dysplastic parenchymal changes with no specific features of carcinoma and ultrasound showed acoustic shadowing but no discrete mass. Excision biopsy of these lumps was performed. Histologically they were benign, and were composed of fibrous tissue with a chronic inflammatory cell infiltrate. With better awareness of fibrous mastopathy which can occur in this group of diabetic patients, and with the absence of specific radiological features of malignancy, some of these women may be observed and spared excision biopsy.
本文报告了两例胰岛素依赖型糖尿病控制不佳的女性病例，她们临床上表现为乳房出现质地硬、边界清晰的肿块，怀疑为癌。乳房X线摄影显示乳腺实质有致密的发育异常改变，但无癌的特异性表现，超声检查显示有声影但无边界清晰的肿块。对这些肿块进行了切除活检。组织学检查显示为良性，由纤维组织和慢性炎症细胞浸润组成。鉴于对这组糖尿病患者可能发生的纤维性乳腺病有了更好的认识，且缺乏恶性肿瘤的特异性影像学特征，部分此类女性患者可进行观察，避免切除活检。
