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[感染性关节切除成形术后患者的髋关节假体再植入术]

[Reimplantation of a hip prosthesis in patients with an infected resection arthroplasty].

作者信息

Klima S, Zeh A, Josten C

机构信息

Klinik für Unfall-, Wiederherstellungs- und Plastische Chirurgie, Universitätsklinikum Leipzig AöR.

出版信息

Z Orthop Unfall. 2008 Sep-Oct;146(5):616-23. doi: 10.1055/s-2008-1038719. Epub 2008 Oct 9.

Abstract

AIM

Resection arthroplasty is an accepted surgical option to treat severe late periprosthetic infections. However, it is known that one has to consider that a persistence of infection is very often combined with a permanent fistula in approximately 10 % of the patients. In particular, the occurrence of a fistula and pain caused by the persistent infection is followed by a considerable reduction of the quality of life of these patients. We have analysed the effort and complications of treatment and the change of pain and function of these patients.

METHOD

In this study 11 patients (average age 68 years) with a Girdlestone situation and persistent infection with an average duration of 33 months were successfully treated by a multiple stage surgical therapy plan which included a radical surgical revision of the infection, stepwise leg lengthening and subsequent reimplantation. In all cases surgical revision of the infection was supported by both systemic and local (antibiotic-loaded cement spacer) antibiotic therapy. The choice of implants followed the general recommendations for revision hip arthroplasty.

RESULTS

The mean follow-up after reimplantation was 16 months (min 4, max 24). We observed an average improvement of the Harris hip score from 27.7 points at the beginning of the therapy to 72.5 points at the end of the follow-up. None of the patients had suffered from a reinfection at the end of the follow-up. We observed no surgically related mortality. Surgical complications including spacer dislocations and implant dislocation were seen. The leg length discrepancy could be decreased from an average of 6.8 cm to 1 cm without the occurrence of a neurological deficit.

CONCLUSION

The reimplantation of a hip prosthesis in cases of infected Girdlestone situations is complex, it can, however, offer the prospect of a marked increase in function and less pain for these patients.

摘要

目的

切除关节成形术是治疗严重晚期人工关节周围感染的一种公认的手术选择。然而,众所周知,必须考虑到在大约10%的患者中,感染持续存在常伴有永久性瘘管。特别是,瘘管的出现以及持续性感染引起的疼痛会导致这些患者的生活质量大幅下降。我们分析了这些患者的治疗努力和并发症以及疼痛和功能的变化。

方法

在本研究中,11例(平均年龄68岁)处于Girdlestone状态且感染持续平均33个月的患者通过多阶段手术治疗方案成功治疗,该方案包括对感染进行彻底的手术翻修、逐步延长腿部以及随后的再植入。在所有病例中,感染的手术翻修均得到全身和局部(抗生素负载骨水泥间隔物)抗生素治疗的支持。植入物的选择遵循髋关节翻修置换术的一般建议。

结果

再植入后的平均随访时间为16个月(最短4个月,最长24个月)。我们观察到Harris髋关节评分从治疗开始时的27.7分平均提高到随访结束时的72.5分。随访结束时,没有患者再次感染。我们未观察到与手术相关的死亡。出现了包括间隔物脱位和植入物脱位在内的手术并发症。腿长差异可从平均6.8厘米降至1厘米,且未出现神经功能缺损。

结论

在感染性Girdlestone状态下进行髋关节假体再植入手术复杂,但可为这些患者提供功能显著改善和疼痛减轻的前景。

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