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以急腹症表现的巨大肝阿米巴脓肿:一例报告

Gigantic hepatic amebic abscess presenting as acute abdomen: a case report.

作者信息

Papavramidis T S, Sapalidis K, Pappas D, Karagianopoulou G, Trikoupi A, Souleimanis C H, Papavramidis S T

机构信息

Department of Surgery, A.H.E.P.A. University Hospital of Thessaloniki, Aristotle's University of Thessaloniki, Thessaloniki, Macedonia, Greece.

出版信息

J Med Case Rep. 2008 Oct 12;2:325. doi: 10.1186/1752-1947-2-325.

Abstract

INTRODUCTION

Amebiasis is a parasitic disease caused by Entamoeba histolytica. It most commonly results in asymptomatic colonization of the gastrointestinal tract, but some patients develop intestinal invasive or extra-intestinal diseases. Liver abscess is the most common extra-intestinal manifestation. The large number of clinical presentations of amebic liver abscess makes the diagnosis very challenging in non-endemic countries. Late diagnosis of the amebic abscess may lead to perforation and amebic peritonitis, resulting in high mortality rates.

CASE PRESENTATION

This report describes a 37-year-old white man, suffering from hepatitis B, with a gigantic amebic liver abscess presenting as an acute abdomen due to its rupture. Rapid deterioration of the patient's condition and acute abdomen led to an emergency operation. A large volume of free fluid together with debris was found at the moment of entry into the peritoneal cavity because of a rupture of the hepatic abscess at the position of the segment VIII. Surgical drainage of the hepatic abscess was performed; two wide drains were placed in the remaining hepatic cavities and one on the right hemithorax. The patient was hospitalized in the ICU for 14 days and for another 14 days in our department. The diagnosis of amebic abscess was made by the pathologists who identified E. histolytica in the debris.

CONCLUSION

Acute abdomen due to a ruptured amebic liver abscess is extremely rare in western countries where the parasite is not endemic. Prompt diagnosis and treatment are fundamental to preserving the patient's life since the mortality rates remain extremely high when untreated, even nowadays.

摘要

引言

阿米巴病是由溶组织内阿米巴引起的寄生虫病。它最常导致胃肠道无症状定植,但一些患者会发展为肠道侵袭性疾病或肠外疾病。肝脓肿是最常见的肠外表现。在非流行国家,阿米巴肝脓肿的大量临床表现使得诊断极具挑战性。阿米巴脓肿的延迟诊断可能导致穿孔和阿米巴性腹膜炎,从而导致高死亡率。

病例介绍

本报告描述了一名37岁的白人男性,患有乙型肝炎,因巨大的阿米巴肝脓肿破裂而表现为急腹症。患者病情迅速恶化和急腹症导致了急诊手术。由于肝脓肿在肝VIII段位置破裂,在进入腹腔时发现大量游离液体和碎屑。对肝脓肿进行了手术引流;在剩余的肝腔中放置了两根宽引流管,在右胸腔放置了一根。患者在重症监护病房住院14天,在我们科室又住院14天。病理学家在碎屑中鉴定出溶组织内阿米巴,从而做出了阿米巴脓肿的诊断。

结论

在寄生虫非地方性流行的西方国家,阿米巴肝脓肿破裂导致的急腹症极为罕见。及时诊断和治疗对于挽救患者生命至关重要,因为即使在当今,未经治疗时死亡率仍然极高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7810/2572068/c869beaa70f6/1752-1947-2-325-1.jpg

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