Sharma Navneet, Sharma Aman, Varma Subhash, Lal Anupam, Singh Virendra
The Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh-160012, India.
BMC Res Notes. 2010 Jan 25;3:21. doi: 10.1186/1756-0500-3-21.
Amoebic Liver abscess although fairly common in developing countries, yet, there is limited data on the clinical presentation to the emergency department. A retrospective analysis of 86 indoor cases of Amoebic Liver Abscess presenting to the emergency department over a 5-year period was carried out.
The mean age of patients was 40.5 +/- 2.1 years (male-female ratio = 7:1). Fever, pain abdomen and diarrhea were seen in 94%, 90% and 10.5% respectively. Duration of symptoms less than 2 weeks was seen in 48% cases. Hepatomegaly was present in 16% cases only, a right sided pleural effusion in 14% cases and ascites in 5.7%. On ultrasound, a right lobe abscess was seen in 65%, a left lobe abscess in 13% and multiple abscesses in both the lobes in 22% cases. Seventy one cases underwent per-cutaneous pigtail catheter drainage for a mean period of 13.4 +/- 0.8 days. The mortality rate was 5.8%. On multivariate regression and correlation analysis, a higher number of inserted pigtail catheters correlated to mortality.
Amoebic liver abscess presents commonly to the emergency department and should be suspected in persons with prolonged fever and pain abdomen. Conservative management for uncomplicated amoebic liver abscess and insertion of single per-cutaneous pigtail catheter drainage for complicated amoebic liver abscess are efficacious as treatment modalities.
阿米巴肝脓肿在发展中国家虽相当常见,但关于其在急诊科的临床表现的数据有限。对5年间在急诊科就诊的86例住院阿米巴肝脓肿病例进行了回顾性分析。
患者的平均年龄为40.5±2.1岁(男女比例为7:1)。发热、腹痛和腹泻的发生率分别为94%、90%和10.5%。48%的病例症状持续时间少于2周。仅16%的病例出现肝肿大,14%的病例出现右侧胸腔积液,5.7%的病例出现腹水。超声检查显示,65%的病例为右叶脓肿,13%为左叶脓肿,22%的病例为两叶多发脓肿。71例患者接受了经皮猪尾导管引流,平均引流时间为13.4±0.8天。死亡率为5.8%。多因素回归和相关性分析显示,插入猪尾导管的数量较多与死亡率相关。
阿米巴肝脓肿常在急诊科就诊,对于长期发热和腹痛的患者应怀疑此病。对于非复杂性阿米巴肝脓肿采用保守治疗,对于复杂性阿米巴肝脓肿采用经皮单猪尾导管引流作为治疗方式是有效的。