Pustovalov A P
Farmakol Toksikol. 1991 Mar-Apr;54(2):50-2.
In hypertension there was shown an increase of the erythrocyte suspension viscosity coefficient, a decrease of the transmural difference of the abdominal aorta potentials and the erythrocyte charge at a lowering of the level of the studied electrolytes in plasma, the abdominal aorta wall and an increase of sodium content in erythrocytes. Heparin corrected the changes in the coefficient of viscosity and charge of erythrocytes, the transmural difference of potentials, potassium and magnesium levels in erythrocytes, sodium level in the abdominal aorta wall induced by hypertension. On the whole there was observed no levelling by heparin of electrolyte imbalance in the erythrocyte-plasma-abdominal aorta wall system.
在高血压患者中,随着血浆、腹主动脉壁中所研究电解质水平的降低以及红细胞中钠含量的增加,红细胞悬浮粘度系数升高,腹主动脉跨壁电位差和红细胞电荷降低。肝素纠正了高血压所致的红细胞粘度系数和电荷、跨壁电位差、红细胞中钾和镁水平以及腹主动脉壁中钠水平的变化。总体而言,未观察到肝素使红细胞-血浆-腹主动脉壁系统中的电解质失衡趋于平稳。