Dorofeev B F, Kholodov L E
Farmakol Toksikol. 1991 Mar-Apr;54(2):66-9.
Pycamilon was shown to be rapidly absorbed in the blood (tmax = 0.23 h), to penetrate well through the blood-brain barrier and to be intensively uptaken by the animal organs and tissues and to be eliminated mainly in the urine (t1/2 = 0.51 h). The drug bioavailability at oral administration to mice is 21.9%, and to rats from 53 to 78.9% (according to the urinary excretion data).
匹卡米隆在血液中吸收迅速（达峰时间=0.23小时），能很好地透过血脑屏障，被动物的器官和组织大量摄取，主要经尿液排泄（半衰期=0.51小时）。小鼠口服给药的药物生物利用度为21.9%，大鼠为53%至78.9%（根据尿排泄数据）。
