Ivashin V M, Chumakova O V, Bandazhevskiĭ Iu I, Oboznyĭ N D, Zakharchenko R G
Farmakol Toksikol. 1991 Mar-Apr;54(2):80-1.
Female mongrel albino rats were administered orally carbophos in a dose of 10 mg/kg (1/100 of LD50) on the 11th, 13th, 15th and 17th days of pregnancy. The antenatal administration of carbophos was shown to produce combined disturbances of the postnatal development of the mongrel albino rats manifesting themselves in changes of the maturation of sensomotor reflexes, cholinesterase activity, increased addiction both to carbophos and ethanol.
在怀孕的第11、13、15和17天,给雌性杂种白化大鼠口服10毫克/千克剂量的敌百虫(LD50的1/100)。产前给予敌百虫显示会对杂种白化大鼠的产后发育产生综合干扰,表现为感觉运动反射成熟度的变化、胆碱酯酶活性的变化、对敌百虫和乙醇的成瘾性增加。