Edlow Jonathan A, Newman-Toker David E, Savitz Sean I
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA 02215, USA.
Lancet Neurol. 2008 Oct;7(10):951-64. doi: 10.1016/S1474-4422(08)70216-3.
Cerebellar infarction is an important cause of stroke that often presents with common and non-specific symptoms such as dizziness, nausea and vomiting, unsteady gait, and headache. Accurate diagnosis frequently relies on careful attention to patients' coordination, gait, and eye movements--components of the neurological physical examination that are sometimes omitted or abridged if cerebellar stroke is not specifically being considered. The differential diagnosis is broad, and includes many common and benign causes. Furthermore, early-stage posterior fossa ischaemia is rarely seen with brain CT--the most commonly available initial imaging test that is used for stroke. Insufficient examination and imaging can result in misdiagnosis. However, early correct diagnosis is crucial to help prevent treatable but potentially fatal complications, such as brainstem compression and obstructive hydrocephalus. The identification and treatment of the underlying vascular lesions at an early stage can also prevent subsequent occurrences of stroke and improve patients' outcomes. Here, we review the clinical presentation of cerebellar infarction, from diagnosis and misdiagnosis to patients' monitoring, treatment, and potential complications.
小脑梗死是中风的一个重要原因,常表现为头晕、恶心、呕吐、步态不稳和头痛等常见且非特异性的症状。准确诊断通常依赖于对患者的协调能力、步态和眼球运动予以仔细关注,而这些神经系统体格检查的内容,如果未特意考虑小脑中风,有时会被省略或简化。鉴别诊断范围广泛,包括许多常见的良性病因。此外,早期后颅窝缺血在脑部CT检查中很少能被发现,而脑部CT是用于中风检查最常用的初始影像学检查手段。检查和影像学检查不足可能导致误诊。然而,早期正确诊断对于预防可治疗但可能致命的并发症(如脑干受压和梗阻性脑积水)至关重要。早期识别并治疗潜在的血管病变也可预防中风的后续发作并改善患者的预后。在此,我们回顾小脑梗死的临床表现,从诊断、误诊到患者的监测、治疗及潜在并发症。