Yang Yang, DeWeese Michael R, Otazu Gonzalo H, Zador Anthony M
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Nat Neurosci. 2008 Nov;11(11):1262-3. doi: 10.1038/nn.2211. Epub 2008 Oct 12.
Neurons in the auditory cortex can lock to the fine timing of acoustic stimuli with millisecond precision, but it is not known whether this precise spike timing can be used to guide decisions. We used chronically implanted microelectrode pairs to stimulate neurons in the rat auditory cortex directly and found that rats can exploit differences in the timing of cortical activity that are as short as 3 ms to guide decisions.
听觉皮层中的神经元能够以毫秒级的精度锁定声音刺激的精确时间,但尚不清楚这种精确的尖峰时间是否可用于指导决策。我们使用长期植入的微电极对直接刺激大鼠听觉皮层中的神经元,发现大鼠能够利用短至3毫秒的皮层活动时间差异来指导决策。