Chen Shih-Hsiang, Liu Li-Yu, Jaing Tang-Her, Tseng Chen-Kan, Lin Kuang-Lin, Lui Tai-Ngar
Division of Hematology and Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Pediatr Hematol Oncol. 2008 Sep;25(7):647-54. doi: 10.1080/08880010802243979.
The authors sought to evaluate the treatment outcome of children with medulloblastoma at a single institution. Forty-two children were analyzed. Eighty-six percent of the children who received chemotherapy were treated with cisplatin-based chemotherapy. No factors were found to affect outcome significantly. Compared with children treated before 1994 at the same institution, the median survival time was significantly longer (40 vs. 25 months, p = .0003). The authors conclude that some improvement of treatment outcome for children with medulloblastoma seemed to be achieved.
作者试图评估在单一机构中髓母细胞瘤患儿的治疗结果。对42名儿童进行了分析。接受化疗的儿童中有86%接受了以顺铂为基础的化疗。未发现有因素对结果有显著影响。与1994年之前在同一机构接受治疗的儿童相比，中位生存时间显著更长（40个月对25个月，p = 0.0003）。作者得出结论，髓母细胞瘤患儿的治疗结果似乎有了一定改善。
