Hodler J, Hunkler H
Bull Schweiz Akad Med Wiss. 1976 Dec;32(4-6):277-89.
The examples of tubular proteinuria, postobstructive diuresis, tubular function in terminal renal failure and the hereditary defects of tubular transport mechanisms are used to demonstrate the difficulty in elucidating defects of renal membrane transports in man. She is caused by the impossibility of applying the appropriate techniques to evaluate membrane functions in man and by the complexity of human disease. The rapidly growing knowledge of physiologic membrane functions in the kidney should however enable some progress in the field of human pathophysiology in a not too remote future.
肾小管性蛋白尿、梗阻后利尿、终末期肾衰竭时的肾小管功能以及肾小管转运机制的遗传性缺陷等例子,被用来证明阐明人类肾膜转运缺陷的困难。这是由于无法应用适当技术评估人类的膜功能以及人类疾病的复杂性所致。然而,肾脏生理膜功能知识的迅速增长,应该会在不太遥远的将来使人在人类病理生理学领域取得一些进展。