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Reduced expression of HLA-DP antigens on PWM stimulated T lymphocytes in patients suffering from psoriasis vulgaris.

作者信息

Buc M, Munozová H, Russ G, Busová B, Vlcek F, Rovenský J

机构信息

Faculty of Medicine, Comenius University Bratislava, Czechoslovakia.

出版信息

Immunobiology. 1991 Mar;182(2):197-204. doi: 10.1016/S0171-2985(11)80204-4.

DOI:10.1016/S0171-2985(11)80204-4
PMID:1885207
Abstract

24 psoriasis vulgaris patients were investigated for the expression of class II HLA antigens on the surface of PWM-stimulated T lymphocytes. The percentage of the expression of HLA-DP antigens ranged from 50.1% to 82.6% compared to a 100% level in healthy controls (p less than 0.005). No significant differences in the expression of HLA-DR antigens were observed. A higher frequency of some HLA antigens was found in the group of patients studied: B13 - 23.1%/6.2%, B 17 - 15.4%/7.1%, and Dw7 - 59.4%/15.8%.

摘要

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