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Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons.
Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16356-61. doi: 10.1073/pnas.0808699105. Epub 2008 Oct 13.
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DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains.
Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):348-53. doi: 10.1073/pnas.2637013100. Epub 2003 Dec 18.
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Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons.
Neuropsychopharmacology. 2011 Jun;36(7):1366-74. doi: 10.1038/npp.2011.21. Epub 2011 Mar 2.
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Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia.
Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12578-83. doi: 10.1073/pnas.0505394102. Epub 2005 Aug 19.
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DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures.
Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1749-54. doi: 10.1073/pnas.0409648102. Epub 2005 Jan 25.
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Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder.
Schizophr Res. 2007 Mar;91(1-3):51-61. doi: 10.1016/j.schres.2006.11.029. Epub 2007 Jan 31.

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Epigenetics: A link between toxicants and diseases.
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DNA methylation at AHRR as a master predictor of smoke exposure and a biomarker for sleep and exercise.
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Epigenetic modifications in abdominal aortic aneurysms: from basic to clinical.
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Visit to visit transition in TXNIP gene methylation and the risk of type 2 diabetes mellitus: a nested case-control study.
J Hum Genet. 2024 Jul;69(7):311-319. doi: 10.1038/s10038-024-01243-8. Epub 2024 Mar 25.
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Developmental nicotine exposure and masculinization of the rat preoptic area.
Neurotoxicology. 2022 Mar;89:41-54. doi: 10.1016/j.neuro.2022.01.005. Epub 2022 Jan 10.

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Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.
Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13614-9. doi: 10.1073/pnas.0805493105. Epub 2008 Aug 29.
2
Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activity.
J Neurosci. 2007 Sep 26;27(39):10508-19. doi: 10.1523/JNEUROSCI.3353-07.2007.
3
The pipeline and future of drug development in schizophrenia.
Mol Psychiatry. 2007 Oct;12(10):904-22. doi: 10.1038/sj.mp.4002062. Epub 2007 Jul 31.
4
Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars.
Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10164-9. doi: 10.1073/pnas.0703806104. Epub 2007 Jun 6.
5
Long-term effects of chronic nicotine exposure on brain nicotinic receptors.
Proc Natl Acad Sci U S A. 2007 May 8;104(19):8155-60. doi: 10.1073/pnas.0702698104. Epub 2007 Apr 30.
6
Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters.
Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4676-81. doi: 10.1073/pnas.0700529104. Epub 2007 Mar 7.
7
Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder.
Schizophr Res. 2007 Mar;91(1-3):51-61. doi: 10.1016/j.schres.2006.11.029. Epub 2007 Jan 31.
9
Ligands selective for alpha4beta2 but not alpha3beta4 or alpha7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat.
Psychopharmacology (Berl). 2007 Feb;190(2):157-70. doi: 10.1007/s00213-006-0596-8. Epub 2006 Nov 18.
10
Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice.
J Pharmacol Exp Ther. 2007 Jan;320(1):250-7. doi: 10.1124/jpet.106.111237. Epub 2006 Oct 4.

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