血液系统肿瘤与癌的同时检测：7例报告
Concomitant detection of hematological neoplasm and carcinoma: report on seven cases.
作者信息
Lira Mariana Montenegro de Melo, Moreira Luciana Regina, Ruano Thais, Quintal Maísa Momesso, Martins Rita de Cássia Perina, Silva Annacarolina Fabiana Lúcia da, Soares Fernando Augusto, Vassallo José
机构信息
Department of Pathology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.
出版信息
Sao Paulo Med J. 2008 Jul;126(4):245-7. doi: 10.1590/s1516-31802008000400013.
CONTEXT
The presence of multiple neoplasms in one patient is an uncommon event. Its occurrence ranges from 1.2% to 4.5% of cancer patients in autopsy and clinical studies. In the present article, cases of synchronous diagnoses of carcinoma and lymphoid neoplasms are reported. The intention of this report was to alert clinicians and pathologists to the possibility of the existence of concomitant neoplasms, in order to prevent inaccurate or delayed diagnosis and staging.
CASES
Seven patients (four female and three male) with a median age of 61.4 years were diagnosed as having concomitant epithelial and hematological neoplasms.
DISCUSSION AND CONCLUSION
Lymph nodes should be carefully examined when searching for metastases, because of the possibility of a second hematological malignancy. Whenever uncommon suspicious morphological features are seen in such neoplasms, an immunohistochemical analysis is essential.
背景
一名患者出现多种肿瘤是罕见事件。在尸检和临床研究中，其发生率在癌症患者中为1.2%至4.5%。在本文中，报告了同时诊断出癌和淋巴瘤的病例。本报告的目的是提醒临床医生和病理学家注意存在并发肿瘤的可能性，以防止诊断和分期不准确或延迟。
病例
7例患者（4例女性和3例男性），中位年龄61.4岁，被诊断患有上皮性和血液学肿瘤。
讨论与结论
在寻找转移灶时，应仔细检查淋巴结，因为可能存在第二种血液系统恶性肿瘤。每当在这类肿瘤中看到不常见的可疑形态特征时，免疫组化分析至关重要。
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