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恶性胃十二指肠梗阻:采用自膨式裸支架治疗

Malignant gastroduodenal obstruction: treatment with self-expanding uncovered wallstent.

作者信息

Gutzeit Andreas, Binkert Christoph A, Schoch Eric, Sautter Thomas, Jost Res, Zollikofer Christoph L

机构信息

Department of Radiology, Kantonsspital Winterthur, Winterthur, Switzerland.

出版信息

Cardiovasc Intervent Radiol. 2009 Jan;32(1):97-105. doi: 10.1007/s00270-008-9445-y. Epub 2008 Oct 15.

DOI:10.1007/s00270-008-9445-y
PMID:18855047
Abstract

PURPOSE

To retrospectively evaluate the clinical effectiveness of a self-expanding uncovered Wallstent in patients with malignant gastroduodenal obstruction.

MATERIALS AND METHODS

Under combined endoscopic and fluoroscopic guidance, 29 patients with a malignant gastroduodenal stenosis were treated with a self-expanding uncovered metallic Wallstent. A dysphagia score was assessed before and after the intervention to measure the success of this palliative therapy. The dysphagia score ranged between grade 0 to grade 4: grade 0 = able to tolerate solid food, grade 1 = able to tolerate soft food, grade 2 = able to tolerate thick liquids, grade 3 = able to tolerate water or clear fluids, and grade 4 = unable to tolerate anything perorally. Stent patency and patients survival rates were calculated.

RESULTS

The insertion of the gastroduodenal stent was technically successful in 28 patients (96.5%). After stenting, 25 patients (86.2%) showed clinical improvement by at least one score point. During follow-up, 22 (78.5%) of 28 patients showed no stent occlusion until death and did not have to undergo any further intervention. In six patients (20.6%), all of whom were treated with secondary stent insertions, occlusion with tumor ingrowth and/or overgrowth was observed after the intervention. The median period of primary stent patency in our study was 240 days.

CONCLUSION

Placement of an uncovered Wallstent is clinically effective in patients with malignant gastroduodenal obstruction. Stent placement is associated with high technical success, good palliation effect, and high durability of stent function.

摘要

目的

回顾性评估自膨式裸金属Wallstent支架治疗胃十二指肠恶性梗阻患者的临床疗效。

材料与方法

在胃镜和透视联合引导下,对29例胃十二指肠恶性狭窄患者采用自膨式裸金属Wallstent支架进行治疗。在干预前后评估吞咽困难评分,以衡量这种姑息治疗的成功率。吞咽困难评分范围为0级至4级:0级 = 能够耐受固体食物,1级 = 能够耐受软食,2级 = 能够耐受浓稠液体,3级 = 能够耐受水或清液,4级 = 经口不能耐受任何食物。计算支架通畅率和患者生存率。

结果

28例患者(96.5%)的胃十二指肠支架置入技术成功。置入支架后,25例患者(86.2%)的临床症状改善至少1分。随访期间,28例患者中有22例(78.5%)直至死亡时未出现支架闭塞,无需进一步干预。6例患者(20.6%)均接受了二次支架置入,干预后观察到肿瘤长入和/或过度生长导致的闭塞。本研究中初次支架通畅的中位时间为240天。

结论

裸金属Wallstent支架置入术治疗胃十二指肠恶性梗阻临床疗效显著。支架置入技术成功率高,缓解效果好,支架功能耐久性高。

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