Isakov I V, Kurtasova L M
Regional Center on Prophylaxis and Combating of AIDS and Infection Diseases, Krasnoyarsk.
Bull Exp Biol Med. 2007 Dec;144(6):810-2. doi: 10.1007/s10517-007-0437-8.
We studied the expression of CD69 antigen on CD8+ lymphocytes in response to nonspecific activator phytohemagglutinin in 202 patients with HIV infection. It was found that the number of CD8+CD69+ lymphocytes in HIV-infected patients increased; this parameter negatively correlated with relative and absolute content of CD4+ cells and positively correlated with IgG concentration.
我们研究了202例HIV感染患者中CD8⁺淋巴细胞上CD69抗原对非特异性激活剂植物血凝素的反应表达。结果发现,HIV感染患者中CD8⁺CD69⁺淋巴细胞数量增加;该参数与CD4⁺细胞的相对和绝对含量呈负相关,与IgG浓度呈正相关。