Lee S Y, Kim J D, Lee Y H, Rhee H, Choi Y S
Department of Food Science and Technology, Kangweon National University, Chuncheon, Republic of Korea.
Life Sci. 1991;49(13):947-51. doi: 10.1016/0024-3205(91)90077-o.
The effects of the methanol extract of Rosa rugosa roots on serum and liver lipids were studied in rats. The rats were fed the purified diets with or without the methanol extract at the 1% level for 4 weeks. The concentrations of serum and liver total cholesterol were not significantly affected by the feeding of extract. Feeding of the extract, on the other hand, reduced the liver triacylglycerol content without influencing the serum triacylglycerol level. The effects of the extract on lipids profiles were diminished markedly by dietary cholesterol. The results suggest an existence of component in the extract which may ameliorate the accumulation of triacylglycerol in rat liver.
研究了玫瑰根甲醇提取物对大鼠血清和肝脏脂质的影响。将大鼠喂食含或不含1%水平甲醇提取物的纯化日粮4周。提取物的喂食对血清和肝脏总胆固醇浓度没有显著影响。另一方面，喂食提取物可降低肝脏三酰甘油含量，而不影响血清三酰甘油水平。日粮胆固醇可显著减弱提取物对脂质谱的影响。结果表明提取物中存在一种成分，可能会改善大鼠肝脏中三酰甘油的积累。
