Whitesides J F, Krista L M, Mora E C, Klesius P H, Gray B W, Spano J S, Drane J W
College of Veterinary Medicine, Auburn University, Alabama 36849.
Poult Sci. 1991 Jun;70(6):1362-71. doi: 10.3382/ps.0701362.
The effects of surgical and chemical in ovo bursectomy on the histology of primary and secondary lymphoid organs were studied in hypertensive and hypotensive lines of turkeys. The effects of bursectomy were measured by determining the presence of lymphatic nodules and the presence of lymphocytes in secondary lymphoid organs: spleen, cecal tonsil, Meckel's diverticulum, and Peyer's patches; as well as in the thymus and bursa of Fabricius. No treatment effect on splenic nodule formation occurred, but a significantly lower lymphocyte density score was present in the surgically bursectomized group. Both nodule formation and lymphocyte density scores for the cecal tonsil and Peyer's patches were significantly reduced in the surgically bursectomized and testosterone-treated groups as compared with the control and sham groups. The most consistent depression in lymphatic scores in both the surgically and chemically bursectomized groups occurred in the Peyer's patches followed by cecal tonsils and Meckel's diverticulum. As expected, there were no differences in thymocyte density scores. There was no consistent effect on lymphatic scores due to blood pressure selection; however, the hypertensive line showed significantly lower scores than the hypotensive line in the bursa, cecal tonsils, and Peyer's patches. No differences between the sexes were noted in any organ.
在高血压和低血压品系的火鸡中，研究了手术切除法和化学法卵内法氏囊切除对一级和二级淋巴器官组织学的影响。通过测定二级淋巴器官（脾脏、盲肠扁桃体、梅克尔憩室和派伊尔氏淋巴集结）以及胸腺和法氏囊中淋巴小结的存在情况和淋巴细胞的存在情况，来衡量法氏囊切除的效果。手术切除法氏囊对脾脏小结形成没有治疗效果，但手术切除法氏囊组的淋巴细胞密度评分显著降低。与对照组和假手术组相比，手术切除法氏囊组和睾酮处理组的盲肠扁桃体和派伊尔氏淋巴集结的小结形成和淋巴细胞密度评分均显著降低。手术切除法氏囊组和化学切除法氏囊组中，派伊尔氏淋巴集结的淋巴评分下降最为一致，其次是盲肠扁桃体和梅克尔憩室。正如预期的那样，胸腺细胞密度评分没有差异。血压选择对淋巴评分没有一致的影响；然而，在法氏囊、盲肠扁桃体和派伊尔氏淋巴集结中，高血压品系的评分显著低于低血压品系。在任何器官中，未观察到性别差异。
